Bosco Luigi, Filoni Sergio
Department of Animal and Human Biology, University of La Sapienza, Via A. Borelli 50, 00161 Rome, Italy.
Department of Biology, University of Tor Vergata, Via G. Carnevale, 00173 Rome, Italy.
Dev Growth Differ. 1992 Dec;34(6):619-625. doi: 10.1111/j.1440-169X.1992.tb00030.x.
The lentectomized eye of larval Xenopus laevis can regenerate a lens by a process of lens-transdifferentiation of the cornea and pericorneal epidermis. These tissues can form the lens only when they become in direct communication with the environment of the vitreous chamber (neural retina) indicating that the eye cup plays a fundamental role in this process. In this work the role of the eye cup in the maintainance of the lens-forming capacity of the cornea and pericorneal epidermis was studied by allowing these tissues to cover the enucleated orbit for different periods, and then implanting them into the vitreous chamber of the contralateral eye. Under these experimental conditions the maintainance of the lens-forming capacity of the cornea and pericorneal epidermis showed no significant correlation with the time from enucleation to implantation.
非洲爪蟾幼体摘除晶状体的眼睛可通过角膜和角膜周表皮的晶状体转分化过程再生晶状体。这些组织只有在与玻璃体腔（神经视网膜）环境直接接触时才能形成晶状体，这表明眼杯在此过程中起着至关重要的作用。在本研究中，通过让这些组织覆盖摘除眼球的眼眶不同时间段，然后将其植入对侧眼的玻璃体腔，研究了眼杯在维持角膜和角膜周表皮形成晶状体能力方面的作用。在这些实验条件下，角膜和角膜周表皮形成晶状体能力的维持与摘除眼球至植入的时间无显著相关性。
