Man W K, Michalowski A, Li S K, Barr J, Burgin J
Agents Actions. 1986 Apr;18(1-2):210-3. doi: 10.1007/BF01988023.
A single dose of 9 or 15 Gy of X-rays was given to the stomach of mice. Gastric histamine formation capacity (HFC) rose in a dose-related fashion during days 4 to 11 after irradiation. This rise coincided with a dose-dependent fall in gastric mural histamine concentration. 15 Gy X-rays also resulted in a transient loss of body weight (days 4-8 after irradiation). These results suggest that irradiation of the stomach mobilizes gastric histamine and that gastric histamine stores may be radiosensitive.
对小鼠胃部给予单次9或15 Gy的X射线照射。照射后第4至11天，胃组胺形成能力（HFC）呈剂量依赖性升高。这种升高与胃壁组胺浓度的剂量依赖性降低同时出现。15 Gy的X射线照射还导致体重短暂下降（照射后第4 - 8天）。这些结果表明，胃部照射会动员胃组胺，并且胃组胺储备可能对辐射敏感。
