疑似 COVID-19 疫苗相关重症肌无力患者出现 Cogan 征。
Cogan's sign in a patient with suspected post-COVID-19 vaccine-associated myasthenia gravis.
机构信息
Universidade Federal do Ceará, Divisão de Neurologia, Departamento de Clínica Médica, Fortaleza, CE, Brasil.
Universidade Estadual do Ceará, Centro de Ciências da Saúde, Fortaleza, CE, Brasil.
出版信息
Rev Soc Bras Med Trop. 2023 Jun 2;56:e0007. doi: 10.1590/0037-8682-0007-2023. eCollection 2023.
The Cogan's sign is indicative of myasthenia gravis. This is the first report of neurological signs in a patient with post-COVID-19 vaccine-associated myasthenia gravis in Brazil. In this case, a previously healthy 68-year-old woman presented with proximal limb weakness, left ptosis, and diplopia 1 month after receiving her fourth dose of the COVID-19 vaccine. Neurological examination revealed the presence of Cogan's sign, and she recovered rapidly after treatment. To our knowledge, this is the first reported case of myasthenia gravis associated with the COVID-19 vaccine in Brazil.
科根氏征提示重症肌无力。这是巴西首例与 COVID-19 疫苗相关的重症肌无力患者出现神经学征象的报告。本例患者为 68 岁女性，既往健康，在接种第四剂 COVID-19 疫苗后 1 个月出现四肢近端无力、左侧上睑下垂和复视。神经系统检查发现存在科根氏征，经治疗后迅速恢复。据我们所知，这是巴西首例与 COVID-19 疫苗相关的重症肌无力病例。
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