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[原发性纵隔B细胞淋巴瘤孕妇的心血管并发症]

[Cardiovascular complications in pregnant woman with Primary Mediastinal B-Cell Lymphoma].

作者信息

Inquilla Coyla Melisa, Anchante Hernández Henry, Medina Palomino Félix

机构信息

Hospital Cayetano Heredia, Lima - Perú. Hospital Cayetano Heredia Lima Perú.

出版信息

Arch Peru Cardiol Cir Cardiovasc. 2022 Jun 27;3(2):112-116. doi: 10.47487/apcyccv.v3i2.202. eCollection 2022 Apr-Jun.

Abstract

A 26-year-old pregnant woman with 29 weeks of gestational age reported two months of cough, dyspnea, orthopnea, and palpitations. Chest tomography revealed a 10x12cm solid mass in the right lung. Echocardiography showed that the tumor compromised the right atrium and ventricle, and was diagnosed by transcutaneous biopsy as Primary Mediastinal B-Cell Lymphoma (PMCBL). The patient presented 2:1 atrial flutter, sinus bradycardia, and ectopic atrial bradycardia. Due to the rapid poor evolution, it was decided to terminate the pregnancy by cesarean section and start chemotherapy, after which the cardiovascular complications resolved. PCML is a very rare lymphoma that can affect pregnant women in any trimester, its symptoms are related to its rapid growth and compromise of the heart, causing various cardiovascular manifestations (heart failure, pericardial effusion, cardiac arrhythmias). PCMLC is characteristically chemosensitive and has a good prognosis.

摘要

一名孕29周的26岁孕妇报告有两个月的咳嗽、呼吸困难、端坐呼吸和心悸症状。胸部断层扫描显示右肺有一个10×12厘米的实性肿块。超声心动图显示肿瘤累及右心房和右心室,经皮活检诊断为原发性纵隔B细胞淋巴瘤(PMCBL)。该患者出现2:1心房扑动、窦性心动过缓和异位房性心动过缓。由于病情迅速恶化,决定通过剖宫产终止妊娠并开始化疗,化疗后心血管并发症得以缓解。原发性纵隔B细胞淋巴瘤是一种非常罕见的淋巴瘤,可在任何孕期影响孕妇,其症状与其快速生长和心脏受累有关,可导致各种心血管表现(心力衰竭、心包积液、心律失常)。原发性纵隔B细胞淋巴瘤对化疗具有特征性敏感性,预后良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a889/10241342/4a996bb1e78a/apcyccv-3-112-g001.jpg

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