Michel-Cherqui Mireille, Ma Sabrina, d'Ussel Marguerite, Ebbo David, Spassova Antoinette, Chaix-Couturier Carine, Szekely Barbara, Fischler Marc, Lemaire Nicolas, Le Guen Morgan
Department of Anesthesiology, Hospital Foch, Suresnes, France.
Department of Medicine, Université Versailles Saint-Quentin en Yvelines, Versailles, France.
Front Neurol. 2023 May 22;14:1193752. doi: 10.3389/fneur.2023.1193752. eCollection 2023.
Use of auriculotherapy to prevent episodic migraine pain has seldom been reported. The aim of this open study was to show that three sessions of auriculotherapy, 1 month apart, using semi-permanent needles decrease frequency and intensity of an attack in patients presenting episodic migraine. A total of 90 patients were randomized to the treatment group (AUR group, = 58) or the control group (C group, = 32). Four patients dropped out during the study (three in the AUR group and one in the C group). The number of days with migraine and non-migraine headache was similar when the analysis focused on the 3 months of the study or on the difference in each group of this number between the 3 months preceding the inclusion and the 3 months of the study ( = 0.123). AUR group patients had fewer days with non-migraine headache ( = 0.011) and took less Triptans ( = 0.045) than group C. Number of days with migraine, sum of the pain intensities of all migraines and non-migraine headaches, and total number of analgesics taken, other than triptan, were similar between groups. MIDAS score decreased with time in the AUR group while it increased in the C group whether in absolute values ( = 0.035) or as categories ( = 0.037). These contrasted results should lead to further study of the effectiveness of auriculotherapy for the prevention of migraine. : Protocol registered on the Clinicaltrials.gov, website (January 30, 2017, NCT03036761).
很少有关于使用耳穴疗法预防发作性偏头痛疼痛的报道。这项开放性研究的目的是表明，使用半永久性针具，每隔1个月进行3次耳穴疗法，可降低发作性偏头痛患者发作的频率和强度。总共90名患者被随机分为治疗组（耳穴疗法组，n = 58）或对照组（C组，n = 32）。在研究期间有4名患者退出（耳穴疗法组3名，C组1名）。当分析聚焦于研究的3个月或每组在纳入前3个月与研究的3个月之间该数字的差异时，偏头痛和非偏头痛性头痛的天数相似（P = 0.123）。与C组相比，耳穴疗法组患者的非偏头痛性头痛天数更少（P = 0.011），服用曲坦类药物的量也更少（P = 0.045）。两组之间偏头痛天数、所有偏头痛和非偏头痛性头痛的疼痛强度总和以及除曲坦类药物外服用的镇痛药总数相似。耳穴疗法组的偏头痛残疾评定量表（MIDAS）评分随时间下降，而C组则上升，无论是绝对值（P = 0.035）还是分类（P = 0.037）。这些对比结果应促使对耳穴疗法预防偏头痛的有效性进行进一步研究。：方案已在Clinicaltrials.gov网站注册（2017年1月30日，NCT03036761）。
