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Lessons learned from a career in neuropathology.从神经病理学职业生涯中汲取的经验教训。
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本文引用的文献

1
Clearance of interstitial fluid (ISF) and CSF (CLIC) group-part of Vascular Professional Interest Area (PIA): Cerebrovascular disease and the failure of elimination of Amyloid-β from the brain and retina with age and Alzheimer's disease-Opportunities for Therapy.间质液（ISF）和脑脊液清除（CLIC）组——血管专业兴趣领域（PIA）的一部分：脑血管疾病以及随着年龄增长和患阿尔茨海默病时大脑和视网膜中β淀粉样蛋白清除失败——治疗机会
Alzheimers Dement (Amst). 2020 Aug 3;12(1):e12053. doi: 10.1002/dad2.12053. eCollection 2020.
2
Cerebrovascular Smooth Muscle Cells as the Drivers of Intramural Periarterial Drainage of the Brain.脑血管平滑肌细胞作为脑壁内动脉周围引流的驱动因素。
Front Aging Neurosci. 2019 Jan 23;11:1. doi: 10.3389/fnagi.2019.00001. eCollection 2019.
3
Convective influx/glymphatic system: tracers injected into the CSF enter and leave the brain along separate periarterial basement membrane pathways.对流内渗/神经淋巴系统：注入 CSF 的示踪剂沿着不同的动脉周围基膜途径进入和离开大脑。
Acta Neuropathol. 2018 Jul;136(1):139-152. doi: 10.1007/s00401-018-1862-7. Epub 2018 May 12.
4
The fine anatomy of the perivascular compartment in the human brain: relevance to dilated perivascular spaces in cerebral amyloid angiopathy.人脑血管周围间隙的精细解剖结构：与脑淀粉样血管病中血管周围间隙扩张的相关性
Neuropathol Appl Neurobiol. 2019 Apr;45(3):305-308. doi: 10.1111/nan.12480. Epub 2018 May 15.
5
Cerebrospinal Fluid Clearance in Alzheimer Disease Measured with Dynamic PET.用动态正电子发射断层扫描测量阿尔茨海默病患者的脑脊液清除率
J Nucl Med. 2017 Sep;58(9):1471-1476. doi: 10.2967/jnumed.116.187211. Epub 2017 Mar 16.
6
The movers and shapers in immune privilege of the CNS.中枢神经系统免疫特权中的推动者和塑造者。
Nat Immunol. 2017 Feb;18(2):123-131. doi: 10.1038/ni.3666. Epub 2017 Jan 16.
7
Review: cerebral amyloid angiopathy, prion angiopathy, CADASIL and the spectrum of protein elimination failure angiopathies (PEFA) in neurodegenerative disease with a focus on therapy.综述：脑淀粉样血管病、朊病毒血管病、CADASIL 及神经退行性疾病中蛋白清除失败性血管病（PEFA）谱，重点介绍治疗方法。
Neuropathol Appl Neurobiol. 2013 Oct;39(6):593-611. doi: 10.1111/nan.12042.
8
Disruption of arterial perivascular drainage of amyloid-β from the brains of mice expressing the human APOE ε4 allele.破坏表达人 APOE ε4 等位基因的小鼠大脑中淀粉样蛋白-β的动脉周围血管排水。
PLoS One. 2012;7(7):e41636. doi: 10.1371/journal.pone.0041636. Epub 2012 Jul 25.
9
Intrastriatal convection-enhanced delivery results in widespread perivascular distribution in a pre-clinical model.纹状体内的对流增强递送导致临床前模型中广泛的血管周围分布。
Fluids Barriers CNS. 2012 Jan 20;9(1):2. doi: 10.1186/2045-8118-9-2.
10
Perivascular drainage of solutes is impaired in the ageing mouse brain and in the presence of cerebral amyloid angiopathy.血管周围溶质的排出在衰老的小鼠大脑和脑淀粉样血管病中受损。
Acta Neuropathol. 2011 Apr;121(4):431-43. doi: 10.1007/s00401-011-0801-7. Epub 2011 Jan 23.

Lessons learned from a career in neuropathology.

作者信息

Weller Roy O

机构信息

Faculty of Medicine, Southampton University, United Kingdom.

出版信息

Free Neuropathol. 2021 Oct 25;2:27. doi: 10.17879/freeneuropathology-2021-3634. eCollection 2021 Jan.

DOI:10.17879/freeneuropathology-2021-3634
PMID:37284630
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10240952/
Abstract
摘要