Gregor Mendel Institute of Molecular Plant Biology, Austrian Academy of Sciences, Vienna, Austria.
Department of Ecology Evolution and Behavior, Faculty of Science, Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel.
PLoS Biol. 2023 Jun 7;21(6):e3002152. doi: 10.1371/journal.pbio.3002152. eCollection 2023 Jun.
Genome integrity in animals depends on silencing of mobile elements by Piwi-interacting RNAs (piRNAs). A new study in this issue of PLOS Biology reveals recent evolutionary losses of key piRNA biogenesis factors in flies, highlighting adaptability by rapid shift to alternative piRNA biogenesis strategies.
动物的基因组完整性依赖于 Piwi 相互作用 RNA(piRNA)对移动元件的沉默。本期《PLOS 生物学》中的一项新研究揭示了果蝇中关键 piRNA 生物发生因子的近期进化缺失,突出了通过快速转向替代 piRNA 生物发生策略的适应性。