Piszker Alexander, McManus Nicholas
Michigan State University College of Osteopathic Medicine, Trinity Health Muskegon Emergency Medicine Residency, Muskegon, Michigan.
Clin Pract Cases Emerg Med. 2023 May;7(2):77-80. doi: 10.5811/cpcem.1401.
Psychosis associated with coronavirus disease 2019 (COVID-19) has been previously, but infrequently, reported in the literature. We present a rare case of COVID-19-associated severe psychosis and suicide attempt in an 80-year-old male with no personal or known family history of psychiatric disease. Our patient's symptoms appeared to be longer lasting than most other reported cases in the available literature.
After a COVID-19 diagnosis, our patient experienced fluctuating, long-lasting psychiatric symptoms over a six-month period. During this time, he was unable to function independently. Suggested mechanisms involve a multifactorial combination of neuroinflammation and increased societal stress due to the direct and indirect effects of the virus, respectively.
More research is needed to help identify risk factors, prognostic indicators, and a standard of care for psychosis associated with COVID-19.
2019年冠状病毒病(COVID-19)相关的精神病此前在文献中有报道,但较为罕见。我们报告一例80岁男性COVID-19相关的严重精神病及自杀未遂病例,该患者无个人或已知家族精神病史。我们患者的症状似乎比现有文献中大多数其他报道的病例持续时间更长。
在确诊COVID-19后,我们的患者在六个月内经历了波动且持久的精神症状。在此期间,他无法独立生活。推测的机制分别涉及病毒的直接和间接作用导致的神经炎症和社会压力增加的多因素组合。
需要更多研究来帮助确定与COVID-19相关的精神病的风险因素、预后指标和护理标准。