Strobino B, Fox H E, Kline J, Stein Z, Susser M, Warburton D
Am J Public Health. 1986 Aug;76(8):986-91. doi: 10.2105/ajph.76.8.986.
Women with a history of recurrent spontaneous abortions (repeaters) are compared with women who have had live births and no spontaneous abortions (multiparae) and women who have had live births and only one spontaneous abortion (sporadics) to identify characteristics of the women and their abortuses that might predict subsequent fetal loss. A number of risk factors for recurrent spontaneous abortion have been identified: the loss of a chromosomally normal conception, loss after the first trimester of pregnancy, a delay in conceiving prior to the study pregnancy, a diagnosis of cervical incompetence, and a history of very low birthweight deliveries. The odds ratios associated with being a repeater vary from 1.4 to 5.6 depending on the number of characteristics present.
将有复发性自然流产史的女性(复发性流产者)与有活产史且无自然流产的女性(经产妇)以及有活产史且仅有一次自然流产的女性(偶发性流产者)进行比较,以确定可能预测后续胎儿丢失的女性及其流产胎儿的特征。已确定了一些复发性自然流产的风险因素:染色体正常妊娠的丢失、妊娠中期后流产、本次研究妊娠前受孕延迟、宫颈机能不全的诊断以及极低出生体重儿分娩史。根据存在的特征数量,与作为复发性流产者相关的优势比在1.4至5.6之间变化。