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针灸对伴有主要精神障碍和相关症状的地震幸存者的影响:临床研究的范围综述。

Effects of acupuncture on earthquake survivors with major psychiatric disorders and related symptoms: A scoping review of clinical studies.

机构信息

Department of Oriental Neuropsychiatry, Dong-Eui University College of Korean Medicine, Busan, Republic of Korea.

College of Korean Medicine, Wonkwang University, Iksan, Republic of Korea.

出版信息

PLoS One. 2023 Jun 8;18(6):e0286671. doi: 10.1371/journal.pone.0286671. eCollection 2023.

DOI:10.1371/journal.pone.0286671
PMID:37289799
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10249843/
Abstract

BACKGROUND

This scoping review aimed to determine the current research status of acupuncture for major psychiatric disorder (MPD) in earthquake survivors.

METHOD

We followed the scoping review process described previously. A literature search on 14 electronic databases was conducted from inception to November 29, 2022. Data from the included studies were collected and descriptively analyzed to address our research question. Extracted data were collated, synthesized, and summarized the according to the analytical framework of a scoping review.

RESULT

This scoping review included nine clinical studies: four randomized controlled trials (RCTs) and five before-after studies. The most frequent MPD type among the included acupuncture studies was posttraumatic stress disorder (PTSD; 6/9, 66.67%). The most frequent acupuncture type was scalp electro-acupuncture (4/9, 44.44%), followed by manual acupuncture and ear acupressure/ear acupuncture (3/9, 33.33%). Studies using scalp electro-acupuncture all used common acupoints, including GB20, GV20, GV24, and EX-HN1. In general, the treatment period lasted between 4 and 12 weeks. Validated assessment tools for PTSD severity and accompanying symptoms were used for patients with PTSD, while the corresponding evaluation tools were used for patients with other diagnoses or clinical symptoms. Acupuncture-related adverse events were generally mild and temporary, such as mild bleeding and hematoma, and syncope was a rare but potentially serious adverse event (1/48 patients and 1/864 sessions over a treatment period of 4 weeks).

CONCLUSION

Acupuncture studies for MPD after an earthquake mainly focused on PTSD. RCTs accounted for around half of the included studies. Scalp electro-acupuncture was the most common acupuncture type, and EX-HN1 and GV24 were the most important acupoints in the acupuncture procedures for MPD. The included studies mostly used validated symptom assessment tools, though some did not. Clinical studies in this field need to be further expanded regardless of the study type.

PROTOCOL REGISTRATION

https://osf.io/wfru7/.

摘要

背景

本范围综述旨在确定地震幸存者重大精神障碍(MPD)的针灸研究现状。

方法

我们遵循了之前描述的范围综述过程。从创建到 2022 年 11 月 29 日,我们在 14 个电子数据库上进行了文献检索。收集纳入研究的数据,并进行描述性分析,以回答我们的研究问题。根据范围综述的分析框架,对提取的数据进行整理、综合和总结。

结果

本范围综述包括 9 项临床研究:4 项随机对照试验(RCT)和 5 项前后对照研究。纳入的针灸研究中最常见的 MPD 类型是创伤后应激障碍(PTSD;6/9,66.67%)。最常见的针灸类型是头皮电针(4/9,44.44%),其次是手动针灸和耳压/耳针(3/9,33.33%)。使用头皮电针的研究均使用了常见穴位,包括 GB20、GV20、GV24 和 EX-HN1。一般来说,治疗期持续 4 至 12 周。PTSD 严重程度和伴随症状的有效评估工具用于 PTSD 患者,而其他诊断或临床症状的患者则使用相应的评估工具。针灸相关的不良事件一般较轻且短暂,如轻度出血和血肿,晕厥是一种罕见但潜在严重的不良事件(4 周治疗期间,48 例患者中有 1 例,864 次治疗中有 1 例)。

结论

地震后针对 MPD 的针灸研究主要集中在 PTSD 上。RCT 约占纳入研究的一半。头皮电针是最常见的针灸类型,EX-HN1 和 GV24 是 MPD 针灸程序中最重要的穴位。纳入的研究大多使用了经过验证的症状评估工具,但也有一些没有。无论研究类型如何,该领域的临床研究都需要进一步扩展。

注册协议

https://osf.io/wfru7/。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e5e/10249843/5c839be13d64/pone.0286671.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e5e/10249843/5c839be13d64/pone.0286671.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e5e/10249843/5c839be13d64/pone.0286671.g001.jpg

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本文引用的文献

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Scalp Acupuncture and Treadmill Training Inhibits Neuronal Apoptosis through Activating cIAP1 in Cerebral Ischemia Rats.头皮针联合跑步机训练通过激活脑缺血大鼠的cIAP1抑制神经元凋亡。
Evid Based Complement Alternat Med. 2021 Nov 12;2021:1418616. doi: 10.1155/2021/1418616. eCollection 2021.
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Treatment Guidelines for PTSD: A Systematic Review.
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J Clin Med. 2021 Sep 15;10(18):4175. doi: 10.3390/jcm10184175.
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The effect of scalp electroacupuncture combined with Memantine in patients with vascular dementia: A retrospective study.头皮电针联合美金刚治疗血管性痴呆患者的疗效:一项回顾性研究。
Medicine (Baltimore). 2020 Aug 14;99(33):e21242. doi: 10.1097/MD.0000000000021242.
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