Division of Minimally Invasive and Gastrointestinal Surgery, Department of Surgery, Medical College of Wisconsin, 8701 W Watertown Plank Rd, Wauwatosa, WI, 53226, USA.
Saint Joseph Hospital, Denver, CO, USA.
Hernia. 2024 Aug;28(4):1069-1075. doi: 10.1007/s10029-023-02817-9. Epub 2023 Jun 8.
Several risk calculators have been developed and deployed to help surgeons estimate the mortality risk that comes with performing hernia repair surgery on patient with severe liver disease. This study seeks to evaluate the accuracy of these risk calculators on patients with cirrhosis and identify the most suitable population of patient to use these calculators on.
The American College of Surgeons National Surgery Quality Improvement Program (NSQIP) 2013-2021 datasets were queried for patients who underwent hernia repair surgery. Mayo Clinic's "Post-operative Mortality Risk in Patients with Cirrhosis" risk calculator, Model for End-Stage Liver Disease (MELD) calculator, NSQIP's Surgical Risk Calculator, and a surgical 5-item modified frailty index were assessed to determine whether they accurately predict mortality following abdominal hernia repair.
In total, 1368 patients met inclusion criteria. Receiver operating characteristic (ROC) curve analysis of the 4 mortality risk calculators resulted in the following: NSQIP Surgical Risk Calculator = 0.803 (p < 0.001); "Post-operative Mortality Risk in Patients with Cirrhosis" with an etiology of "Alcoholic or Cholestatic" yielded an AUC = 0.722 (p < 0.001); MELD score yielded an AUC = 0.709 (p < 0.001); and the modified 5-item frailty index yielded an AUC = 0.583 (p = 0.04).
The NSQIP Surgical Risk Calculator more accurately predicts 30-day mortality in patients with ascites undergoing hernia repair. However, if the patient is missing one of the 21 input variables required by this calculator, Mayo Clinic's 30-day mortality calculator should be consulted before the more widely used MELD score.
已经开发并部署了几种风险计算器,以帮助外科医生估算对患有严重肝脏疾病的患者进行疝修补手术的死亡率风险。本研究旨在评估这些风险计算器在肝硬化患者中的准确性,并确定最适合使用这些计算器的患者人群。
通过美国外科医师学会国家手术质量改进计划(NSQIP)2013-2021 年数据集查询接受疝修补手术的患者。评估 Mayo 诊所的“肝硬化患者术后死亡率风险”风险计算器、终末期肝病模型(MELD)计算器、NSQIP 手术风险计算器和一个手术 5 项修正虚弱指数,以确定它们是否能准确预测腹部疝修补术后的死亡率。
共有 1368 名患者符合纳入标准。4 种死亡率风险计算器的受试者工作特征(ROC)曲线分析结果如下:NSQIP 手术风险计算器 = 0.803(p < 0.001);病因为“酒精性或胆汁淤积性”的“肝硬化患者术后死亡率风险”计算器的 AUC = 0.722(p < 0.001);MELD 评分的 AUC = 0.709(p < 0.001);修正的 5 项虚弱指数的 AUC = 0.583(p = 0.04)。
在有腹水的疝修补患者中,NSQIP 手术风险计算器更准确地预测 30 天死亡率。但是,如果患者缺少这个计算器所需的 21 个输入变量中的一个,则应在使用更广泛的 MELD 评分之前,咨询 Mayo 诊所的 30 天死亡率计算器。