Gold Alexandra K, Otto Michael W
Department of Psychological and Brain Sciences, Boston University, Boston, MA, USA.
Psychiatry Res Commun. 2023 Jun;3(2). doi: 10.1016/j.psycom.2023.100114. Epub 2023 Mar 11.
Increased delay discounting is evident in bipolar disorder, though there is minimal research on the factors that impact delay discounting in this population. We evaluated neurocognitive correlates of delay discounting among relatively euthymic participants with bipolar disorder (N = 76) with ( = 31) and without ( = 45) past-year substance use disorders. There were no significant differences in the mean delay discounting value between the bipolar disorder group and the comorbid bipolar disorder and past-year substance use disorders group ( = .082, Cohen's = 0.41). Using multiple regression, we evaluated the most important predictors of the delay discounting value. Impairments in executive functioning (per number of categories completed on the Wisconsin Card Sorting Test) and visuospatial construction (per the Rey-Osterrieth Complex Figure Test Copy Raw Score), as well as decreased years of education (all < .05), offered the best neurocognitive characterization of increased delay discounting in this sample.
双相情感障碍患者存在延迟折扣增加的现象,不过针对影响该人群延迟折扣的因素所开展的研究极少。我们评估了相对心境平稳的双相情感障碍患者(N = 76)中延迟折扣的神经认知相关性,这些患者中有(n = 31)和没有(n = 45)过去一年的物质使用障碍。双相情感障碍组与双相情感障碍合并过去一年物质使用障碍组之间的平均延迟折扣值无显著差异(p = .082,科恩d值 = 0.41)。通过多元回归分析,我们评估了延迟折扣值的最重要预测因素。执行功能障碍(根据威斯康星卡片分类测验完成的类别数量)和视觉空间构建障碍(根据雷-奥斯特里赫复杂图形测验复制原始得分),以及受教育年限减少(均p < .05),为该样本中延迟折扣增加提供了最佳的神经认知特征描述。