Gerrity Charlotte, Mercadel Alyssa, Alghamdi Abrar, Huang Marilyn
Department of Obstetrics and Gynecology, University of Miami, Miami, FL, United States.
Division of Gynecologic Oncology, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, United States.
Gynecol Oncol Rep. 2023 May 26;47:101212. doi: 10.1016/j.gore.2023.101212. eCollection 2023 Jun.
While Non-Hodgkin Lymphoma (NHL) often involves the ovaries at time of autopsy, it is rarely present at the time of diagnosis. Here we present a case of a 20-year-old who presented with a large adnexal mass and elevated B-HCG, CA-125, and LDH. The patient underwent exploratory laparotomy, and frozen section of the left ovarian mass was suspected to be a dysgerminoma. Final pathologic diagnosis was Ann Arbor stage IVE Diffuse Large B-Cell Lymphoma, germinal center subtype. Patient is currently undergoing chemotherapy and has received the 3 of a planned 6 cycles of R-CHOP.
非霍奇金淋巴瘤(NHL)在尸检时常常累及卵巢,但在诊断时却很少出现。在此,我们报告一例20岁患者,该患者表现为附件区巨大包块,且β-HCG、CA-125和乳酸脱氢酶(LDH)升高。患者接受了剖腹探查术,左侧卵巢肿物的冰冻切片怀疑为无性细胞瘤。最终病理诊断为Ann Arbor分期IVE期弥漫大B细胞淋巴瘤,生发中心亚型。患者目前正在接受化疗,已完成计划的6个周期R-CHOP化疗中的3个周期。