硼酸盐缓冲溶液的抗菌活性。
Antimicrobial activity of borate-buffered solutions.
作者信息
Houlsby R D, Ghajar M, Chavez G O
出版信息
Antimicrob Agents Chemother. 1986 May;29(5):803-6. doi: 10.1128/AAC.29.5.803.
Abstract
A minimal salts medium adjusted to physiological pH and osmolality was buffered with either 0.3% phosphate or 1.2% borate and evaluated for antimicrobial activity. The borate-buffered medium, either with or without a carbon source, exhibited significant antimicrobial activity against 15 Pseudomonas strains, 12 strains of enteric bacteria, and 7 strains of staphylococci. The borate-buffered system appears suitable for use as a generic vehicle for ophthalmic pharmaceutical agents.
摘要
一种调整至生理pH值和渗透压的最低盐培养基，用0.3%的磷酸盐或1.2%的硼酸盐缓冲，并评估其抗菌活性。含或不含碳源的硼酸盐缓冲培养基对15株假单胞菌、12株肠道细菌和7株葡萄球菌表现出显著的抗菌活性。硼酸盐缓冲系统似乎适合用作眼科药剂的通用载体。
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