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Low-molecular-weight proteinase inhibitor of human epidermis inhibiting papain and trypsin activity.

作者信息

Takiuchi I, Takagi H, Goi H, Kawamura M, Higuchi D

出版信息

Arch Dermatol Res. 1986;278(3):194-8. doi: 10.1007/BF00412923.

DOI:10.1007/BF00412923
PMID:3729540
Abstract

A low-molecular-weight proteinase inhibitor was isolated from human epidermal extracts by means of ultrafiltration, gel filtration and ion-exchange chromatography. On polyacrylamide gel electrophoresis (PAGE), the isolated fraction exhibited a single band of activity at pH 9.4, and inhibitory activity against papain and trypsin was detected in this band. Using sodium-dodecyl-sulphate PAGE, the molecular mass of the inhibitor was estimated to be 2,200 daltons.

摘要

相似文献

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Low-molecular-weight proteinase inhibitor in human plasma inhibiting papain and trypsin activity.
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