Gurling H M, Murray R M, Ron M A
Arch Gen Psychiatry. 1986 Aug;43(8):764-7. doi: 10.1001/archpsyc.1986.01800080050007.
Significantly increased brain density was found in the frontal lobes and caudate and thalamic nuclei of monozygotic twins who were severely dependent on alcohol when compared with their normal-drinking co-twins. No significant differences in brain radiodensity were found in a group of identical twins who were discordant for less severe alcoholism. Hemispheric differences in brain density were also examined. Right-handed normal twins had greater density in the left caudate than in the right caudate region; this difference was reduced but still present in alcoholics.
与正常饮酒的同卵双胞胎相比，严重酒精依赖的同卵双胞胎在额叶、尾状核和丘脑核中的脑密度显著增加。在一组酒精中毒程度较轻但不一致的同卵双胞胎中，未发现脑放射性密度有显著差异。还研究了脑密度的半球差异。右利手正常双胞胎的左侧尾状核密度高于右侧尾状核区域；这种差异在酗酒者中有所减小，但仍然存在。
