Gurling H M, Reveley M A, Murray R M
Lancet. 1984 May 5;1(8384):986-8. doi: 10.1016/s0140-6736(84)92326-2.
21 pairs of monozygotic twins discordant for alcoholism and heavy drinking were examined by computerised tomography. Brain and ventricular volumes were calculated by the use of a semiautomated method with the rater blind to twinship and drinking history. 11 severely dependent alcoholics had larger ventricular volumes and ventricle/brain ratios than did their normal cotwins. These changes correlated best with the length of time the alcoholic twin had been drinking eight centilitres pure alcohol, equivalent to a bottle of wine, a day.
对21对患酒精中毒和酗酒程度不同的同卵双胞胎进行了计算机断层扫描检查。采用半自动方法计算脑容量和脑室容量，评分者对双胞胎关系和饮酒史不知情。11名严重酒精依赖者的脑室容量和脑室/脑比率比其正常的双胞胎同胞更大。这些变化与酗酒双胞胎每天饮用相当于一瓶葡萄酒的8厘升纯酒精的时间长短最为相关。
