Park Won-Bin, Cho Jin-Seong, Shin Sang-Do, Kong So-Yeon, Kim Jin-Joo, Lim Yong-Su, Yang Hyuk-Jun, Lee Gun
Department of Emergency Medicine, Gachon University Gil Medical Center, Incheon, Korea.
Department of Emergency Medicine, Seoul National University Hospital, Seoul, Korea.
J Korean Med Sci. 2014 Jul;29(7):985-91. doi: 10.3346/jkms.2014.29.7.985. Epub 2014 Jul 11.
Stroke in young adults has been known to show a lower incidence and a better prognosis. Only a few studies have examined the epidemiology and outcomes of ischemic stroke in young adults and compared them with the elderly in Korean population. All consecutive patients with ischemic stroke visiting 29 participating emergency departments were enrolled from November 2007 to October 2009. Patients with less than 15 yr of age and unknown information on age and confirmed diagnosis were excluded. We categorized the patients into young adults (15 to 45 yr) and elderly (46 yr and older) groups. Of 39,156 enrolled all stroke patients, 25,818 with ischemic stroke were included and analyzed (young adult; n=1,431, 5.5%). Young adult patients showed lower prevalence of most chronic diseases but significantly higher prevalence in exercise, current smoking, and alcohol consumption. Hospital mortality was significantly lower in young adults than elderly (1.1% vs. 3.1%, P<0.001). Higher number of patients in elderly group (68.1%) showed worsening change of modified Rankin Scale than young adults (65.2%). Young adults ischemic stroke showed favorable hospital outcomes than the elderly in Korean population.
已知年轻成年人中风的发病率较低且预后较好。在韩国人群中，仅有少数研究调查了年轻成年人缺血性中风的流行病学和预后情况，并将其与老年人进行比较。2007年11月至2009年10月期间，纳入了所有连续就诊于29个参与研究的急诊科的缺血性中风患者。年龄小于15岁以及年龄和确诊信息不明的患者被排除。我们将患者分为年轻成年人组（15至45岁）和老年人组（46岁及以上）。在39,156名纳入研究的所有中风患者中，有25,818名缺血性中风患者被纳入并进行分析（年轻成年人组；n = 1,431，占5.5%）。年轻成年患者大多数慢性病的患病率较低，但运动、当前吸烟和饮酒的患病率显著较高。年轻成年人的医院死亡率显著低于老年人（1.1%对3.1%，P < 0.001）。老年组中更多患者（68.1%）的改良Rankin量表评分显示病情恶化，高于年轻成年人组（65.2%）。在韩国人群中，年轻成年人缺血性中风的医院结局比老年人更好。
