Perpetuo Lara Helena, Ferreira Wellington, da Silva Danilo Jorge, Jurno Mauro Eduardo, Vale Thiago Cardoso
Programa de Pós-Graduação em Saúde, Faculdade de Medicina, Associação Hospitalar Bom Jesus de Congonhas, Universidade Federal de Juiz de Fora, Congonhas 36415-000, MG, Brazil.
Faculdade de Medicina, Universidade Federal de São João Del Rei, Divinópolis 35501-296, MG, Brazil.
J Clin Med. 2023 May 31;12(11):3789. doi: 10.3390/jcm12113789.
Delirium subsyndrome (SSD) and delirium (DL) are known complications in the intensive care unit (ICU) and are associated with worse clinical outcomes. The aim of this study was to screen for SSD and DL in individuals with COVID-19 admitted to the ICU and to study the associated factors and clinical outcomes.
An observational, longitudinal study was conducted in the reference ICU for COVID-19. All admitted individuals with COVID-19 were screened for SSD and DL during their ICU stay using the Intensive Care Delirium Screening Checklist (ICDSC). Individuals with SSD and/or DL were compared to those without SSD and/or DL.
Ninety-three patients were evaluated, of which 46.7% had SSD and/or DL. The incidence rate was 4.17 cases/100 person-days. Individuals with SSD and/or DL had higher severity of illness on admission to the ICU, as measured by the APACHE II score (median 16 versus 8 points, < 0.001). SSD and/or DL were associated with longer ICU and hospital stays (median 19 versus 6 days, < 0.001 and median 22 versus 7 days, < 0.001, respectively).
Individuals with SSD and/or DL had greater disease severity and longer ICU and hospital stays when compared to those without SSD and/or DL. This reinforces the importance of screening for consciousness disorders in the ICU.
谵妄综合征（SSD）和谵妄（DL）是重症监护病房（ICU）中已知的并发症，且与更差的临床结局相关。本研究的目的是筛查入住ICU的新冠肺炎患者中的SSD和DL，并研究相关因素及临床结局。
在新冠肺炎参考ICU中进行了一项观察性纵向研究。所有入住的新冠肺炎患者在ICU住院期间使用重症监护谵妄筛查清单（ICDSC）进行SSD和DL筛查。将患有SSD和/或DL的患者与未患有SSD和/或DL的患者进行比较。
共评估了93例患者，其中46.7%患有SSD和/或DL。发病率为4.17例/100人日。根据急性生理与慢性健康状况评分系统II（APACHE II）评分，入住ICU时患有SSD和/或DL的患者病情严重程度更高（中位数分别为16分和8分，<0.001）。SSD和/或DL与更长的ICU住院时间和住院时间相关（中位数分别为19天和6天，<0.001；中位数分别为22天和7天，<0.001）。
与未患有SSD和/或DL的患者相比，患有SSD和/或DL的患者疾病严重程度更高，ICU住院时间和住院时间更长。这强化了在ICU中筛查意识障碍的重要性。
