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靶向氧化应激通路的癌症预防与治疗。

Cancer Prevention and Therapy by Targeting Oxidative Stress Pathways.

机构信息

Department of Biotechnology, Institute of Applied Sciences & Humanities, GLA University, Mathura 281406, India.

Department of Physiology and Pharmacology "Vittorio Erspamer", Sapienza University of Rome, 00185 Rome, Italy.

出版信息

Molecules. 2023 May 24;28(11):4293. doi: 10.3390/molecules28114293.

DOI:10.3390/molecules28114293
PMID:37298769
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10254771/
Abstract

Oxidative stress arises from the inadequate production of reactive oxygen species (ROS) which couldn't be neutralized by antioxidant defense [...].

摘要

氧化应激是由于活性氧(ROS)的产生不足,而抗氧化防御系统无法将其中和[... ]。

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The Identification of Prohibitin in the Rat Heart Mitochondria in Heart Failure.心力衰竭大鼠心脏线粒体中抗增殖蛋白的鉴定。
Biomedicines. 2021 Nov 29;9(12):1793. doi: 10.3390/biomedicines9121793.
3
Short overview on the relevance of microRNA-reactive oxygen species (ROS) interactions and lipid peroxidation for modulation of oxidative stress-mediated signalling pathways in cancer treatment.关于微小RNA-活性氧(ROS)相互作用及脂质过氧化在癌症治疗中对氧化应激介导的信号通路调节作用的简要概述。
J Pharm Pharmacol. 2022 Apr 20;74(4):503-515. doi: 10.1093/jpp/rgab045.
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An Overview of Nrf2 Signaling Pathway and Its Role in Inflammation.Nrf2 信号通路概述及其在炎症中的作用。
Molecules. 2020 Nov 23;25(22):5474. doi: 10.3390/molecules25225474.
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Oxidative Stress in Cancer.癌症中的氧化应激。
Cancer Cell. 2020 Aug 10;38(2):167-197. doi: 10.1016/j.ccell.2020.06.001. Epub 2020 Jul 9.
6
SOD2 acetylation on lysine 68 promotes stem cell reprogramming in breast cancer.SOD2 赖氨酸 68 乙酰化促进乳腺癌中的干细胞重编程。
Proc Natl Acad Sci U S A. 2019 Nov 19;116(47):23534-23541. doi: 10.1073/pnas.1902308116. Epub 2019 Oct 7.
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STAT3 and STAT5 Activation in Solid Cancers.实体癌中的信号转导和转录激活因子3(STAT3)及信号转导和转录激活因子5(STAT5)激活
Cancers (Basel). 2019 Sep 25;11(10):1428. doi: 10.3390/cancers11101428.
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