Department of Business Administration, Business School, Al al-Bayt University, Mafraq, Jordan.
Tashkent Institute of Irrigation and Agricultural Mechanization Engineers, Tashkent, Uzbekistan.
Crit Rev Anal Chem. 2024;54(8):3066-3082. doi: 10.1080/10408347.2023.2222412. Epub 2023 Jun 12.
Mycotoxin pollution in agricultural food products endangers animal and human health during the supply chains, therefore the development of accurate and rapid techniques for the determination of mycotoxins is of great importance for food safety guarantee. MXenes-based nanoprobes have attracted enormous attention as a complementary analysis and promising alternative strategies to conventional diagnostic methods, because of their fascinating features, like high electrical conductivity, various surface functional groups, high surface area, superb thermal resistance, good hydrophilicity, and environmentally-friendlier characteristics. In this study, we outline the state-of-the-art research on MXenes-based probes in detecting various mycotoxins like aflatoxin, ochratoxin, deoxynivalenol, zearalenone, and other toxins as a most commonly founded mycotoxin in the agri-food supply chain. First, we present the diverse synthesis approaches and exceptional characteristics of MXenes. Afterward, based on the detecting mechanism, we divide the biosensing utilizations of MXenes into two subcategories: electrochemical, and optical biosensors. Then their performance in effective sensing of mycotoxins is comprehensively deliberated. Finally, present challenges and prospective opportunities for MXenes are debated.
在食品供应链中,农业食品中真菌毒素的污染会危害动物和人类健康,因此开发准确、快速的真菌毒素检测技术对于食品安全保障至关重要。基于 MXenes 的纳米探针因其独特的特性,如高导电性、多种表面官能团、高比表面积、优异的耐热性、良好的亲水性和环境友好性,作为传统诊断方法的补充分析和有前途的替代策略,引起了极大的关注。在这项研究中,我们概述了基于 MXenes 的探针在检测各种真菌毒素(如黄曲霉毒素、赭曲霉毒素、脱氧雪腐镰刀菌烯醇、玉米赤霉烯酮和其他毒素)方面的最新研究进展,这些毒素是农业食品供应链中最常见的真菌毒素。首先,我们介绍了 MXenes 的多种合成方法和卓越特性。然后,根据检测机制,我们将 MXenes 的生物传感应用分为两类:电化学和光学生物传感器。然后,全面讨论了它们在有效检测真菌毒素方面的性能。最后,讨论了 MXenes 目前面临的挑战和未来的机遇。