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青蒿果中活性成分和微量元素对人体某些肝酶的影响。

The Effect of Active Compounds and Trace Elements Extracted from Artemisia Fruit on Some Liver Enzymes in Humans.

机构信息

Department of Chemistry, College of Education for Pure Science (Ibn Al- Haitham), University of Baghdad, Baghdad, Iraq.

出版信息

Arch Razi Inst. 2023 Feb 28;78(1):175-180. doi: 10.22092/ARI.2022.359354.2409. eCollection 2023 Feb.

Abstract

Artemisia is a perennial wild shrub with large branches and compound leaves. Artemisia contains about 400 types, and its medical importance is due to the presence of many active substances and compounds such as volatile oils, alkaloids and flavonoids, glycosides, saponins, tannins, and coumarins. This study was designed to study the effect of the aqueous extract of the fruit of the Artemisia plant on the organs of the body, as well as to know its ability to activate the hepatic enzyme alanine transaminase (ALT/GPT). The fruit of this shrub was extracted using the measurement technique gas chromatography-mass spectrometry (GC/MASS) and organic solvent hexane and ethyl acetate in one to one ratio. It contained 21 compounds, a high percentage of their terpenes, essential aromatic oils, alkaloids, and phenolic compounds. The results showed a significant improvement in the enzyme (ALT/GPT) level after adding different concentrations of hot aqueous extract to the fruit of the Artemisia plant. The fruit of the Artemisia plant can be used to treat many diseases and improve the activity of liver enzymes.

摘要

青蒿是一种多年生野生灌木,有大的分枝和复叶。青蒿含有约 400 种化合物,其医学重要性是由于存在许多活性物质和化合物,如挥发油、生物碱和类黄酮、糖苷、皂甙、鞣质和香豆素。本研究旨在研究青蒿果实水提取物对身体器官的影响,并了解其激活肝酶丙氨酸氨基转移酶(ALT/GPT)的能力。使用气相色谱-质谱联用(GC/MASS)测量技术和有机溶剂正己烷和乙酸乙酯以一比一的比例从这种灌木的果实中提取。它含有 21 种化合物,其中萜类化合物、芳香精油、生物碱和酚类化合物的比例很高。结果表明,向青蒿果实中加入不同浓度的热水提取物后,酶(ALT/GPT)水平显著提高。青蒿的果实可用于治疗许多疾病并提高肝脏酶的活性。

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