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对中国慢性阻塞性肺疾病(COPD)老年患者6分钟步行试验(6MWT)随年龄下降情况的初步评估。

An Initial Assessment of the Decline With Age for the 6-minute Walk Test (6MWT) in Chinese Older Adults With Chronic Obstructive Pulmonary Disease (COPD).

作者信息

Choi Tiffany Ching Man, Tsang Hin Cheung, Lui Sweetie R, Yam Tsz Fung, Lee Yuen Shan, To Yuk Ling, Choo Kah Lin

机构信息

School of Health Sciences, Caritas Institute of Higher Education, Tseung Kwan O, Hong Kong, China.

Department of Physiotherapy, North District Hospital, Sheung Shui, Hong Kong, China.

出版信息

Arch Rehabil Res Clin Transl. 2023 Feb 26;5(2):100262. doi: 10.1016/j.arrct.2023.100262. eCollection 2023 Jun.

DOI:10.1016/j.arrct.2023.100262
PMID:37312980
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10258361/
Abstract

OBJECTIVE

To establish an initial assessment of the decline with age for the 6-minute walk test (6MWT) in patients with chronic obstructive pulmonary disease (COPD) in Chinese older adults.

DESIGN

It was an observational analytical study.

SETTING

The study was conducted in a local acute hospital.

PARTICIPANTS

From January 2017 to January 2021, a total of 525 patients (431 men, 94 women; mean age 73.4±7.9; N=525) with COPD were studied.

MAIN OUTCOME MEASURES

Information including sex, age, Global Initiative for Chronic Obstructive Lung Disease (GOLD) stages, and 6-minute walk distance (6MWD) were collected.

RESULTS

The 6MWD was significantly decreased with increased age (˂0.05). Mean 6MWD in the 61-65 years, 66-70 years, 71-75 years, 76-80 years, 81-85 years, and 86 years or above age groups were 301 m, 305 m, 274 m, 257 m, 260 m, and 215 m, respectively. The difference between the youngest and oldest age groups was 29%. The 6MWD was significantly lower in patients with more severe COPD (˂0.05). The distance decreased from 317 m in GOLD 1, 306 m in GOLD 2, 259 m in GOLD 3 to 167 m in GOLD 4. The percentage dropped in 6MWD from GOLD 1 to GOLD 4 was 47%.

CONCLUSION

An initial assessment of the decline with age for 6MWT in Chinese older adults with COPD has been established. 6MWD decreases as age (in groups 66-75, 81-85, and 86 or above) and COPD severity increases, primarily because of the increased severity of dyspnea, decline in exercise capacity, and muscle changes in aging. Health care professionals in Chinese community can use these values to evaluate these patients' functional capacity, assess treatment effect, and set treatment goals.

摘要

目的

对中国老年慢性阻塞性肺疾病(COPD)患者6分钟步行试验(6MWT)随年龄增长的下降情况进行初步评估。

设计

这是一项观察性分析研究。

地点

研究在当地一家急症医院进行。

参与者

2017年1月至2021年1月,共研究了525例COPD患者(431例男性,94例女性;平均年龄73.4±7.9岁;N = 525)。

主要观察指标

收集性别、年龄、慢性阻塞性肺疾病全球倡议(GOLD)分级以及6分钟步行距离(6MWD)等信息。

结果

6MWD随年龄增长显著下降(P<0.05)。61 - 65岁、66 - 70岁、71 - 75岁、76 - 80岁、81 - 85岁以及86岁及以上年龄组的平均6MWD分别为301米、305米、274米、257米、260米和215米。最年轻和最年长年龄组之间的差异为29%。COPD病情越严重,6MWD越低(P<0.05)。距离从GOLD 1级的317米、GOLD 2级的306米、GOLD 3级的259米降至GOLD 4级的167米。从GOLD 1级到GOLD 4级,6MWD下降的百分比为47%。

结论

已对中国老年COPD患者6MWT随年龄增长的下降情况进行了初步评估。6MWD随着年龄(66 - 75岁、81 - 85岁以及86岁及以上组)和COPD严重程度的增加而降低,主要原因是呼吸困难严重程度增加、运动能力下降以及衰老导致的肌肉变化。中国社区的医护人员可以利用这些数值来评估这些患者的功能能力、评估治疗效果并设定治疗目标。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6ac/10258361/7f0fa68de2bf/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6ac/10258361/3dd1a8e5d3c1/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6ac/10258361/7f0fa68de2bf/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6ac/10258361/3dd1a8e5d3c1/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6ac/10258361/7f0fa68de2bf/gr2.jpg

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