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电阻抗断层成像技术在神经病学中的应用。

Applications of Electrical Impedance Tomography in Neurology.

作者信息

Mirhoseini Mehri, Rezanejad Gatabi Zahra, Das Sayantan, Joveini Sepideh, Rezanezhad Gatabi Iman

机构信息

Amol Faculty of Paramedical Sciences, Mazandaran University of Medical Sciences, Sari, Iran.

Department of Pharmaceutics, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran.

出版信息

Basic Clin Neurosci. 2022 Sep-Oct;13(5):595-608. doi: 10.32598/bcn.2021.3087.1. Epub 2022 Sep 1.

Abstract

INTRODUCTION

Electrical impedance tomography (EIT) is a non-invasive technique utilized in various medical applications, including brain imaging and other neurological diseases. Recognizing the physiological and anatomical characteristics of organs based on their electrical properties is one of the main applications of EIT, as each variety of tissue structure has its own electrical characteristics. The high potential of brain EIT is established in real-time supervision and early recognition of cerebral brain infarction, hemorrhage, and other diseases. In this paper, we review the studies on the neurological applications of EIT.

METHODS

EIT calculates the internal electrical conductivity distribution of an organ by measuring its surface impedance. A series of electrodes are placed on the surface of the target tissue, and small alternating currents are injected. The related voltages are then observed and analyzed. The electrical permittivity and conductivity distributions inside the tissue are reconstructed by measuring the electrode voltages.

RESULTS

The electrical characteristic of biological tissues is remarkably dependent on their structures. Some tissues are better electrical conductors than the others since they have more ions that can carry the electrical charges. This difference is attributed to changes in cellular water content, membrane properties, and destruction of tight junctions within cell membranes.

CONCLUSION

EIT is an extremely practical device for brain imaging, capturing fast electrical activities in the brain, imaging epileptic seizures, detecting intracranial bleeding, detecting cerebral edema, and diagnosing stroke.

摘要

引言

电阻抗断层成像(EIT)是一种非侵入性技术,用于各种医学应用,包括脑成像和其他神经系统疾病。基于器官的电学特性识别其生理和解剖特征是EIT的主要应用之一,因为每种组织结构都有其自身的电学特性。脑EIT在实时监测和早期识别脑梗死、脑出血等疾病方面具有很大潜力。在本文中,我们综述了EIT在神经学应用方面的研究。

方法

EIT通过测量器官表面阻抗来计算其内部电导率分布。将一系列电极放置在目标组织表面,注入小交变电流。然后观察和分析相关电压。通过测量电极电压来重建组织内部的电容率和电导率分布。

结果

生物组织的电学特性显著依赖于其结构。一些组织比其他组织是更好的电导体,因为它们有更多可携带电荷的离子。这种差异归因于细胞含水量、膜特性的变化以及细胞膜内紧密连接的破坏。

结论

EIT是一种用于脑成像的极其实用的设备,可捕捉大脑中的快速电活动、对癫痫发作进行成像、检测颅内出血、检测脑水肿以及诊断中风。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7117/10258591/683208db260f/BCN-13-595-g001.jpg

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