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T-B 细胞协作在自身免疫、感染和移植中的作用。

T-B Collaboration in Autoimmunity, Infection, and Transplantation.

机构信息

Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard, Cambridge, MA.

Department of Pathology, Brigham and Women's Hospital, Boston, MA.

出版信息

Transplantation. 2024 Feb 1;108(2):386-398. doi: 10.1097/TP.0000000000004671. Epub 2024 Jan 19.

Abstract

We have attempted here to provide an up-to-date review of the collaboration between helper T cells and B cells in response to protein and glycoprotein antigens. This collaboration is essential as it not only protects from many pathogens but also contributes to a litany of autoimmune and immune-mediated diseases.

摘要

我们在这里试图提供一个最新的综述,探讨辅助性 T 细胞和 B 细胞在对蛋白质和糖蛋白抗原的反应中的相互协作。这种协作是至关重要的,因为它不仅可以预防许多病原体,还会导致一系列自身免疫和免疫介导的疾病。

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