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疫苗接种和公共卫生措施对加拿大新冠病例影响的反事实分析:可能发生了什么?

Counterfactuals of effects of vaccination and public health measures on COVID-19 cases in Canada: What could have happened?

作者信息

Ogden Nicholas H, Turgeon Patricia, Fazil Aamir, Clark Julia, Gabriele-Rivet Vanessa, Tam Theresa, Ng Victoria

机构信息

Public Health Risk Sciences Division, National Microbiology Laboratory, Public Health Agency of Canada, St-Hyacinthe, QC and Guelph, ON.

Office of the Chief Public Health Officer, Public Health Agency of Canada, Ottawa, ON.

出版信息

Can Commun Dis Rep. 2022 Jul 7;48(7-8):292-302. doi: 10.14745/ccdr.v48i78a01.

DOI:10.14745/ccdr.v48i78a01
PMID:37334255
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10275398/
Abstract

This study illustrates what may have happened, in terms of coronavirus disease 2019 (COVID-19) infections, hospitalizations and deaths in Canada, had public health measures not been used to control the COVID-19 epidemic, and had restrictions been lifted with low levels of vaccination, or no vaccination, of the Canadian population. The timeline of the epidemic in Canada, and the public health interventions used to control the epidemic, are reviewed. Comparisons against outcomes in other countries and counterfactual modelling illustrate the relative success of control of the epidemic in Canada. Together, these observations show that without the use of restrictive measures and without high levels of vaccination, Canada could have experienced substantially higher numbers of infections and hospitalizations and almost a million deaths.

摘要

本研究阐明了在加拿大,如果未采取公共卫生措施来控制2019冠状病毒病(COVID-19)疫情,且在加拿大人口疫苗接种率低或未接种疫苗的情况下就解除限制,那么在COVID-19感染、住院和死亡方面可能会发生什么情况。本文回顾了加拿大疫情的时间线以及用于控制疫情的公共卫生干预措施。与其他国家的结果进行比较以及反事实建模表明了加拿大在控制疫情方面取得的相对成功。这些观察结果共同表明,如果不采取限制性措施且没有高疫苗接种率,加拿大可能会出现数量大幅更多的感染和住院病例,以及近100万例死亡。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dd7/10275398/fa87ccc7a298/487801-f4.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dd7/10275398/fa87ccc7a298/487801-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dd7/10275398/a0957046b9f7/487801-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dd7/10275398/59c06abb19c5/487801-f2.jpg
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2
Estimated Effectiveness of COVID-19 Vaccines Against Omicron or Delta Symptomatic Infection and Severe Outcomes.奥密克戎或德尔塔变异株感染及重症的 COVID-19 疫苗有效性评估。
JAMA Netw Open. 2022 Sep 1;5(9):e2232760. doi: 10.1001/jamanetworkopen.2022.32760.
3
Severity of omicron variant of concern and effectiveness of vaccine boosters against symptomatic disease in Scotland (EAVE II): a national cohort study with nested test-negative design.
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J Med Internet Res. 2024 Aug 13;26:e51325. doi: 10.2196/51325.
4
A methodology for estimating SARS-CoV-2 importation risk by air travel into Canada between July and November 2021.一种估算 2021 年 7 月至 11 月期间通过航空旅行进入加拿大的 SARS-CoV-2 输入风险的方法。
BMC Public Health. 2024 Apr 19;24(1):1088. doi: 10.1186/s12889-024-18563-1.
5
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PLoS One. 2024 Apr 4;19(4):e0297093. doi: 10.1371/journal.pone.0297093. eCollection 2024.
6
Quantifying the economic gains associated with COVID-19 vaccination in the Canadian population: A cost-benefit analysis.量化加拿大人群中与新冠病毒疫苗接种相关的经济收益:成本效益分析。
Can Commun Dis Rep. 2023 Jun 1;49(6):263-273. doi: 10.14745/ccdr.v49i06a03.
7
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苏格兰关注的奥密克戎变异株的严重程度和疫苗加强针预防有症状疾病的效果(EAVE II):一项具有巢式病例对照研究设计的全国队列研究。
Lancet Infect Dis. 2022 Jul;22(7):959-966. doi: 10.1016/S1473-3099(22)00141-4. Epub 2022 Apr 22.
4
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Clin Infect Dis. 2022 Nov 30;75(11):1980-1992. doi: 10.1093/cid/ciac290.
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Environ Res. 2022 Aug;211:113038. doi: 10.1016/j.envres.2022.113038. Epub 2022 Feb 26.
7
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8
An infectious SARS-CoV-2 B.1.1.529 Omicron virus escapes neutralization by therapeutic monoclonal antibodies.一种传染性 SARS-CoV-2 B.1.1.529 奥密克戎病毒能够逃避治疗性单克隆抗体的中和作用。
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