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地中海斑疹热作为伊朗东南部的一种非地方性疾病:基于特定皮肤病变的诊断与治疗

Mediterranean spotted fever as a non-endemic disease in the southeast of Iran: Diagnosis and treatment based on specific skin lesion.

作者信息

Farrokhnia Mehrdad, Shafieipour Sara, Nakhaie Mohsen, Rukerd Mohammad Rezaei Zadeh

机构信息

Infectious and Tropical Research Center Kerman University of Medical Sciences Kerman Iran.

Gastroenterology and Hepatology Research Center, Institute of Basic and Clinical Physiology Sciences Kerman University of Medical Sciences Kerman Iran.

出版信息

Clin Case Rep. 2023 Jun 17;11(6):e7577. doi: 10.1002/ccr3.7577. eCollection 2023 Jun.

DOI:10.1002/ccr3.7577
PMID:37334342
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10276244/
Abstract

KEY CLINICAL MESSAGE

Rickettsia spp. should be investigated if Tache Noire, as a dark plaque covering a superficial ulcer surrounded by scale, edema, and erythema, are observed, even in non-endemic areas of Rickettsia spp.

ABSTRACT

A 31-year-old man with fever, dyspnea, abdominal pain, and jaundice has been admitted to the hospital in the southeast of Iran. Due to the presence of a pathognomonic skin lesion (Tache noire), the patient was diagnosed with Mediterranean spotted fever (MSF) and was treated with doxycycline, without waiting for PCR and IFA findings.

摘要

关键临床信息

即使在立克次体属非流行地区,如果观察到黑痂疹(Tache Noire),即覆盖浅表溃疡且周围有鳞屑、水肿和红斑的黑色斑块,就应调查立克次体属。

摘要

一名31岁男性,有发热、呼吸困难、腹痛和黄疸症状,已入住伊朗东南部的医院。由于存在特征性皮肤病变(黑痂疹),该患者被诊断为地中海斑疹热(MSF),并在未等待聚合酶链反应(PCR)和间接荧光抗体试验(IFA)结果的情况下接受了强力霉素治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c480/10276244/677d56998957/CCR3-11-e7577-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c480/10276244/677d56998957/CCR3-11-e7577-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c480/10276244/677d56998957/CCR3-11-e7577-g001.jpg

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2
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Trop Med Infect Dis. 2021 Sep 24;6(4):172. doi: 10.3390/tropicalmed6040172.
3
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Iran J Microbiol. 2020 Jun;12(3):256-260.