An Electric Light Orchestra in the Brain: Optogenetics for Controlling Seizures via Modulation of Astrocyte Activity.
作者信息
Eyal Sara
机构信息
Institute for Drug Research and the David R. Bloom Centre for Pharmacy and Dr. Adolf and Klara Brettler Center for Research in Molecular Pharmacology and Therapeutics, - The Hebrew University of Jerusalem.
出版信息
Epilepsy Curr. 2023 Mar 29;23(3):188-190. doi: 10.1177/15357597231160600. eCollection 2023 May-Jun.
Abstract
摘要
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本文引用的文献
1
Optogenetics for light control of biological systems.
Nat Rev Methods Primers. 2022;2. doi: 10.1038/s43586-022-00136-4. Epub 2022 Jul 21.
2
Identification of astrocyte regulators by nucleic acid cytometry.
Nature. 2023 Feb;614(7947):326-333. doi: 10.1038/s41586-022-05613-0. Epub 2023 Jan 4.
3
In silico screening for clinical efficacy of antiseizure medications: Not all central nervous system drugs are alike.
Epilepsia. 2023 Feb;64(2):311-319. doi: 10.1111/epi.17479. Epub 2022 Dec 27.
4
Activated astrocytes attenuate neocortical seizures in rodent models through driving Na-K-ATPase.
Nat Commun. 2022 Nov 21;13(1):7136. doi: 10.1038/s41467-022-34662-2.
5
Astrocytes in the initiation and progression of epilepsy.
Nat Rev Neurol. 2022 Dec;18(12):707-722. doi: 10.1038/s41582-022-00727-5. Epub 2022 Oct 24.
6
The Emerging Nature of Astrocyte Diversity.
Annu Rev Neurosci. 2019 Jul 8;42:187-207. doi: 10.1146/annurev-neuro-070918-050443.
7
Implicating Interneurons: Optogenetic Studies Suggest That Interneurons Are Guilty of Contributing to Epileptiform Activity.
Epilepsy Curr. 2015 Jul-Aug;15(4):213-6. doi: 10.5698/1535-7511-15.4.213.
8
Optogenetics and epilepsy: past, present and future.
Epilepsy Curr. 2015 Jan-Feb;15(1):34-8. doi: 10.5698/1535-7597-15.1.34.
9
Photopharmacology: beyond proof of principle.
J Am Chem Soc. 2014 Feb 12;136(6):2178-91. doi: 10.1021/ja413063e. Epub 2014 Feb 4.
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