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印度泰米尔纳德邦成年男性人口中心血管疾病危险因素流行情况及 10 年发病风险评估——基于第五次国家家庭健康调查的分析。

Prevalence of risk factors and estimation of 10-year risk for cardiovascular diseases among male adult population of Tamil Nadu India-an insight from the National Family Health Survey-5.

机构信息

The Wellcome Trust Research Laboratory, Division of Gastrointestinal Sciences, Christian Medical College Vellore, Tamil Nadu, 632002, India.

Department of Community Health, Christian Medical College Vellore, Tamil Nadu, 632002, India.

出版信息

Indian Heart J. 2023 Jul-Aug;75(4):251-257. doi: 10.1016/j.ihj.2023.06.003. Epub 2023 Jun 17.

Abstract

OBJECTIVE

Cardiovascular diseases (CVD) are one of the most addressed preventable diseases of public health importance. However, the risk estimates and use of these risk scores for CVD prevention are the least explored areas. So, in this study, we explored the different categories of Framingham heart study (FHS) 10-year-CVD risk score and their associated factors among the adult male population in Tamil Nadu, India.

METHODS

We used the risk factor level data for male adults aged 18 years and above from the National Family Health Survey (NFHS-5) of Tamil Nadu state, India. Sociodemographic variables, behavioral factors, and physiological/biochemical factors were considered as the risk factor and were estimated using the world health organization (WHO) STEPS categories. FHS 10-year-CVD risk score was calculated using a body-mass index-based published Cox regression equation.

RESULTS

Out of 2289 adult males, only 1.12% of the participants had a 10-year CVD risk score greater than 30% and ∼4% of the total participants require statin treatment (FRS-CVD risk score ≥20). Educational status (aOR:14.21, 95 CI: 4.36-46.22- no formal schooling when compared to 10th and above standard), weekly fruit intake (aOR:0.51, 95 CI: 0.27-0.97 when compared to daily fruit intake) and abdominal obesity (aOR:2.43, 95 CI: 1.58-3.74) were found to be associated with higher FRS scores when adjusted for all other factors not involved in FRS calculation.

CONCLUSION

Widespread use of this score needs to be encouraged in clinical practices and patients with a higher risk of CVD events should be counselled for lifestyle modifications and compliance with treatment for decreasing the burden due to CVDs.

摘要

目的

心血管疾病(CVD)是公共卫生领域最受关注的可预防疾病之一。然而,CVD 预防风险评估和这些风险评分的使用仍是探索最少的领域。因此,在这项研究中,我们探讨了印度泰米尔纳德邦成年男性中不同类别的弗雷明汉心脏研究(FHS)10 年 CVD 风险评分及其相关因素。

方法

我们使用了印度泰米尔纳德邦国家家庭健康调查(NFHS-5)中年龄在 18 岁及以上的男性成年人的风险因素水平数据。社会人口统计学变量、行为因素和生理/生化因素被视为风险因素,并使用世界卫生组织(WHO)的 STEPS 类别进行估计。FHS 10 年 CVD 风险评分使用基于体重指数的发表的 Cox 回归方程进行计算。

结果

在 2289 名成年男性中,只有 1.12%的参与者 10 年 CVD 风险评分大于 30%,约 4%的总参与者需要他汀类药物治疗(FRS-CVD 风险评分≥20)。与接受 10 年级及以上标准教育的人相比,教育程度(OR:14.21,95%CI:4.36-46.22-未接受正规教育)、每周水果摄入量(OR:0.51,95%CI:0.27-0.97 与每天摄入水果相比)和腹型肥胖(OR:2.43,95%CI:1.58-3.74)与更高的 FRS 评分相关,在调整所有未纳入 FRS 计算的其他因素后。

结论

需要鼓励在临床实践中广泛使用该评分,并且应该为 CVD 事件风险较高的患者提供生活方式改变和治疗依从性的咨询,以减轻 CVD 带来的负担。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad28/10421976/01f51e7d704d/gr1.jpg

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