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儿科医生对特殊需求儿童的格氏药物的认知:一项区域性调查。

Pediatricians' awareness of galenic drugs for children with special needs: a regional survey.

机构信息

Department of Medicine, Surgery, and Health Sciences, University of Trieste, Trieste, Italy.

Pharmacy and Clinical Pharmacology Department, Institute for Maternal and Child Health - IRCCS Burlo Garofolo, Trieste, Italy.

出版信息

Ital J Pediatr. 2023 Jun 19;49(1):76. doi: 10.1186/s13052-023-01462-3.

Abstract

The prevalence of children with medical complexity is increasing, therefore drug formulations must be updated in accordance with their needs. Furthermore, a different drug formulation may be also needed for patients who require a very low dosage which is not easily reachable with those of the industrial products or for those following a ketogenic diet. Galenic (or compounded) drugs have been recently pointed out as effective in treating children. Nonetheless, their knowledge among healthcare providers is limited. We investigated how much did pediatricians know about galenic compounds by a short questionnaire administered to family and hospital pediatricians and pediatric residents in Friuli Venezia Giulia, Italy. We collected answers from 65 family pediatricians (57,5%), 39 hospital pediatricians (36,1%), and 47 pediatric residents (41,2%). Overall, both family and hospital pediatricians substantially know what is a galenic compound and the indications to its use. Of note, most of pediatricians ignore which is the legislation that allows the galenic compounds' preparation and use, and which is the correct procedure to prescribe them. Moreover, half of the hospital pediatricians and one-third of the family ones erroneously stated that galenic formulations cost more or like the industrial products, and around the 15% of both categories affirmed that galenic compounds are less safe than the commercial product. In conclusion, the use of galenic drug may significantly improve children's and caregivers' quality of life. We believe that all pediatricians should be updated on this quite new and interesting topic.

摘要

患有复杂疾病的儿童的患病率正在增加,因此必须根据他们的需求更新药物制剂。此外,对于需要极低剂量且工业产品无法轻易达到的患者,或者对于遵循生酮饮食的患者,可能也需要不同的药物制剂。最近有人指出,药剂学(或复合)药物在治疗儿童方面非常有效。尽管如此,医疗保健提供者对它们的了解有限。我们通过向意大利弗留利-威尼斯朱利亚的家庭医生和医院儿科医生以及儿科住院医师发放简短问卷,调查了儿科医生对药剂学化合物的了解程度。我们共收到了 65 名家庭儿科医生(57.5%)、39 名医院儿科医生(36.1%)和 47 名儿科住院医师(41.2%)的回答。总的来说,家庭医生和医院儿科医生都非常了解什么是药剂学化合物以及使用它的适应症。值得注意的是,大多数儿科医生都忽略了允许制备和使用药剂学化合物的立法以及开处方的正确程序。此外,一半的医院儿科医生和三分之一的家庭儿科医生错误地认为,药剂学制剂的成本更高或与工业产品相当,约有 15%的家庭和医院医生认为药剂学化合物不如商业产品安全。总之,使用药剂学药物可以显著提高儿童及其照顾者的生活质量。我们认为,所有儿科医生都应该了解这个相当新颖和有趣的话题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dccd/10280911/f08cd0c83b1b/13052_2023_1462_Fig1_HTML.jpg

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