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老年妇科肿瘤患者化疗起始时的生活质量。

Quality of life of older gynecologic oncology patients at the initiation of chemotherapy.

机构信息

Department of Nursing and Health Promotion, Faculty of Health Sciences, OsloMet - Oslo Metropolitan University, Oslo, Norway.

School of Nursing, University of California, San Francisco, California, USA.

出版信息

Nurs Open. 2023 Oct;10(10):6749-6757. doi: 10.1002/nop2.1921. Epub 2023 Jun 19.

DOI:10.1002/nop2.1921
PMID:37337353
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10495706/
Abstract

AIM

To evaluate older gynecologic oncology patients' quality of life (QOL) at the initiation of chemotherapy and compare their QOL scores with a female age-matched general population (GP) sample.

DESIGN

Cross-sectional.

METHODS

Older (n = 122) gynecologic oncology patients completed the European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire (QLQ-C30) that evaluates global health and five functional scales (range from 0 to 100). Differences in QOL scores between our sample and the GP were evaluated using one-sample t-tests and effect sizes were calculated using Cohen's d.

RESULTS

Patients' mean age was 70.7 years (±6.6). Mean scores for the function scales ranged from 58.5 (±31.1) for role function to 86.1 (±17.0) for cognitive function. Compared to the GP, our sample reported significantly lower scores for global health status, social, role and physical functioning, and a significantly higher score for cognitive functioning. No differences were found in emotional functioning scores.

PATIENT OR PUBLIC CONTRIBUTION

No patient or public contribution.

摘要

目的

评估化疗起始时老年妇科肿瘤患者的生活质量(QOL),并将其 QOL 评分与女性年龄匹配的一般人群(GP)样本进行比较。

设计

横断面研究。

方法

122 名老年妇科肿瘤患者完成了欧洲癌症研究与治疗组织生活质量问卷(QLQ-C30),该问卷评估了总体健康状况和五个功能量表(范围为 0 到 100)。使用单样本 t 检验评估我们的样本与 GP 之间的 QOL 评分差异,并使用 Cohen's d 计算效应大小。

结果

患者的平均年龄为 70.7±6.6 岁。功能量表的平均评分范围从角色功能的 58.5±31.1 到认知功能的 86.1±17.0。与 GP 相比,我们的样本报告全球健康状况、社会、角色和身体功能的评分明显较低,认知功能的评分明显较高。在情感功能评分方面没有差异。

患者或公众的贡献

无患者或公众贡献。

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本文引用的文献

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Distinctions Between Self-Report and Performance-Based Measures of Physical Function in Older Patients Prior to Chemotherapy.老年癌症患者化疗前身体功能的自我报告与基于表现的测量方法之间的差异。
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Functional recovery in older women undergoing surgery for gynaecological malignancies: A systematic review and narrative synthesis.老年妇科恶性肿瘤手术患者的功能恢复:系统评价和叙述性综合。
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Older Patients (Still) Left Out of Cancer Clinical Trials.老年患者(仍然)被排除在癌症临床试验之外。
JAMA. 2019 Nov 12;322(18):1751-1753. doi: 10.1001/jama.2019.17016.
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Current state of quality of life and patient-reported outcomes research.当前生活质量和患者报告结局研究的现状。
Eur J Cancer. 2019 Nov;121:55-63. doi: 10.1016/j.ejca.2019.08.016. Epub 2019 Sep 24.
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PLoS One. 2019 Mar 8;14(3):e0213263. doi: 10.1371/journal.pone.0213263. eCollection 2019.
9
Association Between Symptom Burden and Physical Function in Older Patients with Cancer.老年癌症患者症状负担与身体功能的关系。
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Older ovarian cancer survivors report lower long-term health-related quality of life than younger survivors: A study from the population-based profiles registry.老年卵巢癌幸存者报告称,其长期健康相关生活质量低于年轻幸存者:一项基于人群特征登记的研究。
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