肺I期腺癌的细胞学发现：对早期肺癌检测的意义
Cytologic findings in stage I adenocarcinoma of the lung: implications for the detection of early lung cancer.
作者信息
Bjornsson J, Goellner J R, Williams D E, Scheiber M V
出版信息
J Cancer Res Clin Oncol. 1986;111(3):289-90. doi: 10.1007/BF00389247.
Abstract
Preoperative cytologic examinations were performed on bronchial material from 92 patients with postsurgical (pathologic) stage I (American Joint Committee) adenocarcinoma of the lung. All patients were followed up for at least 5 years or until death; thus, cases of adenocarcinoma metastatic to the lungs were virtually excluded. Only 22 patients (24%) had abnormal preoperative cytologic findings. This low cytologic sensitivity is ascribed to the small size and peripheral location of the tumors. Large lesions of high histologic grades were more likely to have positive preoperative cytologic findings than small, well-differentiated ones.
摘要
对92例术后（病理）I期（美国联合委员会）肺腺癌患者的支气管材料进行了术前细胞学检查。所有患者均随访至少5年或直至死亡；因此，几乎排除了肺转移性腺癌病例。只有22例患者（24%）术前细胞学检查结果异常。这种低细胞学敏感性归因于肿瘤的小尺寸和外周位置。高组织学分级的大病变比小的、高分化的病变更有可能术前细胞学检查结果为阳性。
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