Hoffmann Timothy D, Kurze Elisabeth, Liao Jieren, Hoffmann Thomas, Song Chuankui, Schwab Wilfried
Biotechnology of Natural Products, Technische Universität München, Freising, Germany.
State Key Laboratory of Tea Plant Biology and Utilization, Anhui Agricultural University, Hefei, Anhui, China.
Front Plant Sci. 2023 Jun 6;14:1191625. doi: 10.3389/fpls.2023.1191625. eCollection 2023.
Tea () has been an immensely important commercially grown crop for decades. This is due to the presence of essential nutrients and plant secondary metabolites that exhibit beneficial health effects. UDP-glycosyltransferases (UGTs) play an important role in the diversity of such secondary metabolites by catalysing the transfer of an activated sugar donor to acceptor molecules, and thereby creating a huge variety of glycoconjugates. Only in recent years, thanks to the sequencing of the tea plant genome, have there been increased efforts to characterise the UGTs in to gain an understanding of their physiological role and biotechnological potential. Based on the conserved plant secondary product glycosyltransferase (PSPG) motif and the catalytically active histidine in the active site, UGTs of family 1 in are identified here, and shown to cluster into 21 groups in a phylogenetic tree. Building on this, our current understanding of recently characterised UGTs (CsUGTs) is highlighted and a discussion on future perspectives made.
几十年来,茶叶一直是一种极其重要的商业种植作物。这是因为它含有对健康有益的必需营养素和植物次生代谢产物。尿苷二磷酸糖基转移酶(UGTs)通过催化活化糖供体向受体分子的转移,从而产生多种多样的糖缀合物,在这类次生代谢产物的多样性中发挥着重要作用。直到近年来,由于茶树基因组测序的完成,人们才加大了对茶树中UGTs进行表征的力度,以了解它们的生理作用和生物技术潜力。基于保守的植物次生产物糖基转移酶(PSPG)基序和活性位点中具有催化活性的组氨酸,本文鉴定了茶树中1家族的UGTs,并显示它们在系统发育树中聚为21组。在此基础上,本文强调了我们目前对最近表征的茶树UGTs(CsUGTs)的理解,并对未来的研究方向进行了讨论。