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犬肾中儿茶酚胺含量的神经元和非神经元作用

Neuronal and nonneuronal contributions to renal catecholamine content in the dog.

作者信息

Petrovic T, Anderson W P, Bell C

出版信息

J Neurochem. 1986 Aug;47(2):423-5. doi: 10.1111/j.1471-4159.1986.tb04518.x.

DOI:10.1111/j.1471-4159.1986.tb04518.x
PMID:3734787
Abstract

Endogenous noradrenaline and 3,4-dihydroxyphenylethylamine (dopamine) levels were measured in different zones of the dog kidney following chronic unilateral renal denervation. In outer and inner renal cortex, and in outer medulla, greater than 95% of the tissue content of both catecholamines was contributed by renal nerves, whereas in inner medulla only nonneuronal catecholamines were found. The amounts of neuronal dopamine present in outer renal cortex were greater than would be expected for a population of solely noradrenergic nerves.

摘要

在慢性单侧肾去神经支配后,测定了犬肾不同区域内源性去甲肾上腺素和3,4-二羟基苯乙胺(多巴胺)的水平。在外肾皮质和内肾皮质以及外髓质中,两种儿茶酚胺的组织含量超过95%由肾神经提供,而在内髓质中仅发现非神经元性儿茶酚胺。外肾皮质中存在的神经元多巴胺量比仅含去甲肾上腺素能神经群体预期的量要多。

相似文献

1
Neuronal and nonneuronal contributions to renal catecholamine content in the dog.犬肾中儿茶酚胺含量的神经元和非神经元作用
J Neurochem. 1986 Aug;47(2):423-5. doi: 10.1111/j.1471-4159.1986.tb04518.x.
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Vesicular storage of 3,4-dihydroxyphenylethylamine and noradrenaline in terminal sympathetic nerves of dog spleen and kidney.3,4-二羟基苯乙胺和去甲肾上腺素在犬脾脏和肾脏终末交感神经中的囊泡储存。
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A study of the neuronal and non-neuronal stores of dopamine in rat and rabbit kidney.大鼠和兔肾脏中多巴胺的神经元和非神经元储存研究。
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Further studies on renal nerve stimulation induced release of noradrenaline and dopamine from the canine kidney in situ.肾神经刺激诱导犬原位肾脏释放去甲肾上腺素和多巴胺的进一步研究。
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引用本文的文献

1
Dopamine is metabolised by different enzymes along the rat nephron.多巴胺在大鼠肾单位中由不同的酶进行代谢。
Pflugers Arch. 2005 Jun;450(3):185-91. doi: 10.1007/s00424-005-1386-6. Epub 2005 Apr 30.
2
Effects on renal sympathetic axons in dog of acute 6-hydroxydopamine treatment in combination with selective neuronal uptake inhibitors.急性6-羟基多巴胺治疗联合选择性神经元摄取抑制剂对犬肾交感神经轴突的影响。
Br J Pharmacol. 1990 Apr;99(4):655-60. doi: 10.1111/j.1476-5381.1990.tb12985.x.