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猪对 HPAI 病毒 H5N1 属 2.3.4.4b 系实验感染的低易感性。

Low Susceptibility of Pigs against Experimental Infection with HPAI Virus H5N1 Clade 2.3.4.4b.

出版信息

Emerg Infect Dis. 2023 Jul;29(7):1492-1495. doi: 10.3201/eid2907.230296.

DOI:10.3201/eid2907.230296
PMID:37347930
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10310384/
Abstract

We found that nasal and alimentary experimental exposure of pigs to highly pathogenic avian influenza virus H5N1 clade 2.3.4.4b was associated with marginal viral replication, without inducing any clinical manifestation or pathological changes. Only 1 of 8 pigs seroconverted, pointing to high resistance of pigs to clade 2.3.4.4b infection.

摘要

我们发现，猪经鼻腔和消化道实验感染高致病性禽流感病毒 H5N1 2.3.4.4b 株后，病毒复制量较少，没有引起任何临床症状或病理变化。8 头猪中只有 1 头发病，表明猪对 2.3.4.4b 株感染具有较高的抵抗力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0ed/10310384/3da1af181d15/23-0296-F.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0ed/10310384/3da1af181d15/23-0296-F.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0ed/10310384/3da1af181d15/23-0296-F.jpg

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