多发性硬化症中的脑干听觉诱发电位：与视觉诱发电位、体感诱发电位及脑脊液免疫球蛋白的关系。

Brain-stem auditory evoked potentials in multiple sclerosis: the relation to VEP, SEP and CSF immunoglobulins.

作者信息

Sand T, Sjaastad O, Romslo I, Sulg I

机构信息

Department of Neurology, Regionsykehuset, Trondheim University Hospital, Norway.

出版信息

J Neurol. 1990 Oct;237(6):376-8. doi: 10.1007/BF00315663.

DOI:10.1007/BF00315663

PMID:2277273

Abstract

One hundred patients with multiple sclerosis (MS) were analysed retrospectively with respect to investigations of brain-stem auditory evoked potentials (BAEP), pattern reversal visual evoked potentials (VEP), somatosensory evoked potentials (SEP), and cerebrospinal fluid immunoglobulins (CSF-IG). BAEP were abnormal in 42% of those with normal VEP and SEP examinations, and in 38% of patients with normal CSF-IG. The chance of obtaining at least one abnormal EP was lower in patients with normal CSF-IG than in patients with abnormal CSF. When a "dispersion ratio" was included in the criteria for BAEP abnormality, the sensitivity increased compared with conventional BAEP criteria. We recommend that BAEP should still be included in the EP test battery for patients with suspected MS.

摘要

对100例多发性硬化症（MS）患者进行了回顾性分析，涉及脑干听觉诱发电位（BAEP）、图形翻转视觉诱发电位（VEP）、体感诱发电位（SEP）以及脑脊液免疫球蛋白（CSF-IG）检查。在VEP和SEP检查正常的患者中，42%的患者BAEP异常；在CSF-IG正常的患者中，38%的患者BAEP异常。CSF-IG正常的患者获得至少一项异常诱发电位的几率低于CSF异常的患者。当将“离散率”纳入BAEP异常标准时，与传统BAEP标准相比，敏感性有所提高。我们建议，对于疑似MS的患者，BAEP仍应纳入诱发电位检测项目中。