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使用深吸气屏气乳腺水模对 ExacTrac 动态深吸气屏气流程进行初步端到端测试。

Initial end-to-end testing of the ExacTrac dynamic deep inspiration breath hold workflow using a breath hold breast phantom.

机构信息

School of Physics, Mathematics, and Computing, Faculty of Engineering and Mathematical Sciences, University of Western Australia, Crawley, WA, 6009, Australia.

GenesisCare, 24 Salvado Road, Wembley, WA, 6014, Australia.

出版信息

Phys Eng Sci Med. 2023 Sep;46(3):1239-1247. doi: 10.1007/s13246-023-01291-y. Epub 2023 Jun 22.

Abstract

ExacTrac Dynamic (ETD) provides a Deep Inspiration Breath Hold (DIBH) workflow for breast patients. Stereoscopic x-ray imaging combined with optical and thermal mapping allows localisation against simulation imaging, alongside surface guided breath hold monitoring. This work aimed to determine appropriate imaging parameters, the optimal Hounsfield Unit (HU) threshold for patient contour generation and workflow evaluation via end-to-end (E2E) positioning using a custom breast DIBH phantom. After localisation via existing Image Guidance (IG), stereoscopic imaging was performed with a range of parameters to determine best agreement. Similarly, residual errors in prepositioning were minimised using a range of HU threshold contours. E2E positioning was completed for clinical workflows allowing residual isocentre position error measurement and existing IG comparison. Parameters of 60 kV and 25mAs were determined appropriate for patient imaging and HU thresholds between -600 HU and -200 HU enabled adequate prepositioning. The average and standard deviation in residual isocentre position error was 1.0 ± 0.9 mm, 0.4 ± 1.0 mm and 0.1 ± 0.5 mm in the lateral, longitudinal and vertical directions, respectively. Errors measured using existing IG were -0.6 ± 1.1 mm, 0.5 ± 0.7 mm and 0.2 ± 0.4 mm in the lateral, longitudinal and vertical directions, and 0.0 ± 1.0, 0.5 ± 1.7 and -0.8 ± 1.8 for pitch roll and yaw. The use of bone weighted matching increased residual error, while simulated reduction of DIBH volume maintained isocentre positioning accuracy despite anatomical changes. This initial testing indicated suitability for clinical implementation during DIBH breast treatments.

摘要

ExacTrac Dynamic(ETD)为乳房患者提供了 Deep Inspiration Breath Hold(DIBH)工作流程。立体 X 射线成像与光学和热图相结合,可在模拟成像的基础上进行定位,同时进行表面引导的呼吸暂停监测。这项工作旨在通过使用定制的乳房 DIBH 体模进行端到端(E2E)定位,确定合适的成像参数、用于生成患者轮廓的最佳亨氏单位(HU)阈值,并对工作流程进行评估。在通过现有图像引导(IG)进行定位后,使用一系列参数进行立体成像,以确定最佳一致性。同样,通过使用一系列 HU 阈值轮廓,最大限度地减少了预定位的残余误差。完成了临床工作流程的 E2E 定位,允许测量残余等中心位置误差并进行现有 IG 比较。60kV 和 25mAs 的参数被确定为适合患者成像,HU 阈值在-600 HU 和-200 HU 之间可以实现充分的预定位。横向、纵向和垂直方向上的残余等中心位置误差的平均值和标准差分别为 1.0±0.9mm、0.4±1.0mm 和 0.1±0.5mm。使用现有 IG 测量的误差分别为横向、纵向和垂直方向上的-0.6±1.1mm、0.5±0.7mm 和 0.2±0.4mm,以及 Pitch Roll 和 Yaw 上的 0.0±1.0mm、0.5±1.7mm 和-0.8±1.8mm。骨加权匹配的使用增加了残余误差,而模拟减少 DIBH 体积则保持了等中心定位的准确性,尽管存在解剖变化。这项初步测试表明,它适合在 DIBH 乳房治疗期间进行临床实施。

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