Teich L, Franke D, Michaelis A, Dähnert I, Gebauer R A, Markel F, Paech C
Department for Pediatric Cardiology, University of Leipzig - Heart Center, Leipzig, Germany.
Arbeitskreis Integrierte Informationssysteme, Westsächsische Hochschule Zwickau, Zwickau, Saxony, Germany.
Front Pediatr. 2023 May 23;11:1185629. doi: 10.3389/fped.2023.1185629. eCollection 2023.
The Apple Watch valuably records event-based electrocardiograms (iECG) in children, as shown in recent studies by Paech et al. In contrast to adults, though, the automatic heart rhythm classification of the Apple Watch did not provide satisfactory results in children. Therefore, ECG analysis is limited to interpretation by a pediatric cardiologist. To surmount this difficulty, an artificial intelligence (AI) based algorithm for the automatic interpretation of pediatric Apple Watch iECGs was developed in this study.
A first AI-based algorithm was designed and trained based on prerecorded and manually classified i.e., labeled iECGs. Afterward the algorithm was evaluated in a prospectively recruited cohort of children at the Leipzig Heart Center. iECG evaluation by the algorithm was compared to the 12-lead-ECG evaluation by a pediatric cardiologist (gold standard). The outcomes were then used to calculate the sensitivity and specificity of the Apple Software and the self-developed AI.
The main features of the newly developed AI algorithm and the rapid development cycle are presented. Forty-eight pediatric patients were enrolled in this study. The AI reached a specificity of 96.7% and a sensitivity of 66.7% for classifying a normal sinus rhythm.
The current study presents a first AI-based algorithm for the automatic heart rhythm classification of pediatric iECGs, and therefore provides the basis for further development of the AI-based iECG analysis in children as soon as more training data are available. More training in the AI algorithm is inevitable to enable the AI-based iECG analysis to work as a medical tool in complex patients.
如佩希等人最近的研究所表明的,苹果手表能够有效地记录儿童基于事件的心电图(iECG)。然而,与成人不同的是,苹果手表的自动心律分类在儿童中并未提供令人满意的结果。因此,心电图分析仅限于由儿科心脏病专家进行解读。为克服这一困难,本研究开发了一种基于人工智能(AI)的算法,用于自动解读儿科苹果手表iECG。
基于预先记录并经人工分类即标记的iECG设计并训练了首个基于AI的算法。随后,在莱比锡心脏中心前瞻性招募的儿童队列中对该算法进行评估。将算法对iECG的评估与儿科心脏病专家进行的12导联心电图评估(金标准)进行比较。然后使用这些结果来计算苹果软件和自行开发的AI的敏感性和特异性。
介绍了新开发的AI算法的主要特征和快速的开发周期。本研究纳入了48名儿科患者。该AI在分类正常窦性心律时的特异性达到96.7%,敏感性达到66.7%。
本研究提出了首个用于儿科iECG自动心律分类的基于AI的算法,因此一旦有更多训练数据,就为儿童基于AI的iECG分析的进一步发展提供了基础。为使基于AI的iECG分析能够作为复杂患者的医疗工具发挥作用,对AI算法进行更多训练是不可避免的。