Schuller D E, Fritsch M H
J Surg Oncol. 1986 Jul;32(3):156-8. doi: 10.1002/jso.2930320308.
The purpose of this study was to evaluate the role of triple endoscopy in the routine diagnostic evaluation of head and neck cancer patients to (1) ascertain the accuracy and safety of this approach in identifying multiple neoplasms and (2) determine if such an approach is justifiable rather than relying on radiographic examinations coupled with the routine head and neck exam including indirect laryngoscopy. In this series, the incidence of second malignancies was found to be 11.3%, consistent with other reports in the medical literature. There were no complications noted as a result of triple endoscopy. There were no instances where the second malignancy was not diagnosed prior to triple endoscopy with either the physical exam or routine roentgenograms. There were no incidences where the treatment program of the primary tumor was altered by the information obtained at triple endoscopy. The results of this single institutional study suggest that triple endoscopy need not be a routine component of the diagnostic evaluation of every patient with head and neck cancer. However, every patient should probably have a thorough physical examination coupled with chest and esophageal roentgenograms to search for a simultaneous secondary neoplasm.
本研究的目的是评估三联内镜检查在头颈部癌患者常规诊断评估中的作用，以（1）确定该方法在识别多个肿瘤方面的准确性和安全性，以及（2）确定这种方法是否合理，而不是依赖于影像学检查以及包括间接喉镜检查在内的常规头颈部检查。在本系列研究中，发现第二原发恶性肿瘤的发生率为11.3%，与医学文献中的其他报道一致。三联内镜检查未发现并发症。在三联内镜检查之前，通过体格检查或常规X线检查未诊断出第二原发恶性肿瘤的情况不存在。三联内镜检查所获信息未改变原发肿瘤治疗方案的情况也不存在。这项单机构研究的结果表明，三联内镜检查不必成为每例头颈部癌患者诊断评估的常规组成部分。然而，每位患者可能都应接受全面的体格检查以及胸部和食管X线检查，以寻找同时存在的继发肿瘤。
