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早期气管切开术在危重症新冠肺炎患者中的应用:一项系统评价。

Utility of Early Tracheostomy in Critically Ill Covid-19 Patients: A Systematic Review.

作者信息

Bhasarkar Ashwin, Dolma Kunzes

机构信息

New Delhi, India Vardhman Mahavir Medical College and Safdarjung Hospital.

出版信息

Indian J Otolaryngol Head Neck Surg. 2023 Mar 15;75(3):1-11. doi: 10.1007/s12070-022-03280-1.

Abstract

COVID 19 has proven itself to be an agent of cataclysm and caused an uproar worldwide due to consistent strain on the finite resources available to tackle the situation. With the rapidly mutating viral nature, resultant disease is becoming more severe over time, causing significant numbers of critical cases needing invasive ventilatory support. Available literature dictates that tracheostomy might reduce the stress over healthcare infrastructure. Our systematic review is aimed towards understanding the influence of tracheostomy timing, over the course of the illness, by analyzing the relevant literature, thus aiding in decision making while managing critical COVID 19 patients. With predefined inclusion and exclusion criteria, PubMed data was explored using search terms like 'timing', 'tracheotomy'/'tracheostomy' and 'COVID'/'COVID-19'/'SARS CoV2' and 26 articles were finalised for formal review. 26 studies (3527 patients) were systematically reviewed. 60.3% and 39.5% patients underwent percutaneous dilational tracheostomy and open surgical tracheostomy respectively. We report 7.62%, 21.3%, 56% and 46.53% as approximate estimates, of complication rate, mortality rate, rate of mechanical ventilation weaning and rate of decannulation following tracheostomy in COVID 19 patients, respectively taking into account underestimation of the data. Provided that appropriate preventive measures and safety guidelines are strictly followed, moderately early tracheostomy (between 10 and 14 days of intubation) can prove quite efficacious in management of critical COVID 19 patients. Also, early tracheostomy was associated with early weaning and decannulation, thus reducing the enormous competition for intensive care unit beds.

摘要

事实证明,新冠病毒是一场灾难的始作俑者,由于应对这一情况的有限资源持续紧张,它在全球引发了轩然大波。随着病毒性质迅速变异,由此产生的疾病随着时间的推移变得越来越严重,导致大量危重症患者需要有创通气支持。现有文献表明,气管切开术可能会减轻医疗保健基础设施的压力。我们的系统评价旨在通过分析相关文献,了解气管切开术时机在疾病过程中的影响,从而在管理新冠危重症患者时辅助决策。根据预先设定的纳入和排除标准,使用“时机”“气管切开术”以及“新冠”“新冠病毒病”“严重急性呼吸综合征冠状病毒2”等检索词对PubMed数据进行了检索,最终确定26篇文章进行正式评价。对26项研究(3527例患者)进行了系统评价。分别有60.3%和39.5%的患者接受了经皮扩张气管切开术和开放性手术气管切开术。考虑到数据存在低估情况,我们分别报告新冠患者气管切开术后的并发症发生率、死亡率、机械通气撤机率和拔管率约为7.62%、21.3%、56%和46.53%。如果严格遵循适当的预防措施和安全指南,适度早期气管切开术(插管后10至14天)在管理新冠危重症患者方面可能会非常有效。此外,早期气管切开术与早期撤机和拔管相关,从而减少了对重症监护病房床位的巨大竞争。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ee1/10447350/c6426ea6dd7a/12070_2022_3280_Fig1_HTML.jpg

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