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肥胖对微创冠状动脉旁路移植术围手术期影响及其手术技术的研究

A study on the perioperative effects of obesity on minimally invasive coronary artery bypass grafting and its surgical techniques.

作者信息

Liu Jia-Ji, Liang Lin, Kong Qing-Yu, Ma Xiao-Long, Chi Li-Qun, Lai Yong-Qiang

机构信息

Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing, China.

出版信息

Interdiscip Cardiovasc Thorac Surg. 2023 Jun 1;36(6). doi: 10.1093/icvts/ivad092.

Abstract

OBJECTIVES

The aim of this study was to discuss the perioperative effects of obesity on minimally invasive coronary artery bypass grafting (CABG) and its surgical techniques.

METHODS

A total of 582 patients with multivessel lesion who underwent off-pump CABG by our medical group of Beijing Anzhen Hospital between January 2017 and January 2021 were divided into the minimally invasive cardiac surgery (MICS) group and the conventional group (median sternotomy) according to the surgical method used. The body mass index of the patients was calculated, based on which both groups were divided into obese (≥28 kg/m2) and non-obese subgroups (<28 kg/m2). First, the perioperative data of the obese subgroups of both MICS and conventional groups were compared. Second, the obese and non-obese subgroups were compared in the MICS group.

RESULTS

Despite a higher proportion of diabetes in the MICS group, there was no significant difference in preoperative baseline nor in the incidence of major complications within 30 days after surgery between obese subgroups of the MICS and conventional groups. The MICS group had a significantly lower rate of poor wound healing, along with a higher predischarge Barthel Index. Also, the preoperative baseline between the obese and non-obese subgroups of the MICS group exhibited no statistical differences. The obese subgroup had longer postoperative ventilator assistance, while other intraoperative data and postoperative observation indexes exhibited no significant differences.

CONCLUSIONS

MICS CABG method is safe and feasible for obese patients with multivessel lesion. Minimally invasive surgery is beneficial to wound healing in obese patients. However, it requires a thorough preoperative evaluation and adequate surgical experience and skills.

摘要

目的

本研究旨在探讨肥胖对微创冠状动脉旁路移植术(CABG)围手术期的影响及其手术技巧。

方法

选取2017年1月至2021年1月间在北京安贞医院医疗团队接受非体外循环CABG的582例多支血管病变患者,根据手术方式分为微创心脏手术(MICS)组和传统组(正中开胸)。计算患者的体重指数,并据此将两组再分为肥胖(≥28 kg/m²)和非肥胖亚组(<28 kg/m²)。首先,比较MICS组和传统组肥胖亚组的围手术期数据。其次,比较MICS组内肥胖和非肥胖亚组。

结果

尽管MICS组糖尿病比例较高,但MICS组和传统组肥胖亚组术前基线及术后30天内主要并发症发生率无显著差异。MICS组伤口愈合不良率显著较低,出院前Barthel指数较高。此外,MICS组肥胖和非肥胖亚组术前基线无统计学差异。肥胖亚组术后呼吸机辅助时间较长,而其他术中数据和术后观察指标无显著差异。

结论

MICS CABG方法对于多支血管病变的肥胖患者是安全可行的。微创手术有利于肥胖患者的伤口愈合。然而,这需要全面的术前评估以及足够的手术经验和技巧。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8804/10310502/c711b7f87a15/ivad092f3.jpg

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