Vijayakumar Sathya, Raja Lavanya, Venkatesan Srinivasadesikan, Lin Ming-Chang, Vediappen Padmini
Department of Organic Chemistry, School of Chemistry, Madurai Kamaraj University, Madurai, Tamilnadu, 625021, India.
School of Applied Science and Humanities, Department of Chemistry, Vignan's Foundation for Science, Technology and Research, Vadlamudi, Guntur, Andhra Pradesh, 522 213, India.
J Fluoresc. 2024 Mar;34(2):787-794. doi: 10.1007/s10895-023-03298-w. Epub 2023 Jun 27.
A simple imine derivative based sensor (IDP) has been synthesized and characterized by H NMR, C NMR and mass spectral techniques. IDP is more capable of detecting perfluorooctanoic acid (PFOA) in a selective and sensitive manner. The PFOA as a biomarker interacts with IDP and shows "TURN-ON" response by colorimetric and fluorimetric method. Under optimized experimental observations, the selective determination of PFOA using IDP among other competitors as biomolecules has been noticed. The detection limit is 0.31 × 10 mol/L. The practical applications of the IDP is effectively evaluated in human biofluids and water samples.
一种基于简单亚胺衍生物的传感器（IDP）已通过核磁共振氢谱（¹H NMR）、核磁共振碳谱（¹³C NMR）和质谱技术进行了合成与表征。IDP更能够以选择性和灵敏的方式检测全氟辛酸（PFOA）。作为生物标志物的PFOA与IDP相互作用，并通过比色法和荧光法显示出“开启”响应。在优化的实验条件下，已注意到使用IDP在其他作为生物分子的竞争物中对PFOA进行选择性测定。检测限为0.31×10⁻⁶ mol/L。IDP在人体生物流体和水样中的实际应用得到了有效评估。
