Bhaskar P A, Vanchilingam S, Bhaskar E A, Devaprabhu A, Ganesan R A
Neurology. 1986 Aug;36(8):1119-21. doi: 10.1212/wnl.36.8.1119.
In 47 patients with Parkinson's disease, we studied the visual evoked potential (VEP) using the pattern-reversal checkerboard (CBVEP) and the grating (GVEP) stimuli before and after 3 months of L-dopa therapy. The P100 latency in both CBVEP and GVEP was prolonged before L-dopa therapy, usually commensurate with the degree of motor disability. Clinical improvement of the parkinsonian state after L-dopa therapy was associated with shortening of the P100 latency in CBVEP, but not significantly in GVEP.
在47例帕金森病患者中，我们在左旋多巴治疗3个月前后，使用模式翻转棋盘格（CBVEP）和光栅（GVEP）刺激研究了视觉诱发电位（VEP）。在左旋多巴治疗前，CBVEP和GVEP中的P100潜伏期均延长，通常与运动障碍程度相称。左旋多巴治疗后帕金森状态的临床改善与CBVEP中P100潜伏期缩短相关，但在GVEP中无显著相关性。
