Department of Drug and Health Sciences, University of Catania, 95125 Catania, Italy.
CERNUT-Research Centre for Nutraceuticals and Health Products, University of Catania, 95125 Catania, Italy.
Int J Mol Sci. 2023 Jun 15;24(12):10185. doi: 10.3390/ijms241210185.
Several studies have highlighted the ability of snail mucus in maintaining healthy skin conditions due to its emollient, regenerative, and protective properties. In particular, mucus derived from has already been reported to have beneficial properties such as antimicrobial activity and wound repair capacity. In order to enhance the beneficial effects of snail mucus, a formulation enriched with antioxidant compounds derived from edible flower waste ( L., L., L., L., and Lam.) was obtained. UVB damage was used as a model to investigate in vitro the cytoprotective effects of snail mucus and edible flower extract. Results demonstrated that polyphenols from the flower waste extract boosted the antioxidant activity of snail mucus, providing cytoprotective effects in keratinocytes exposed to UVB radiation. Additionally, glutathione content, reactive oxygen species (ROS), and lipid peroxidation levels were reduced following the combined treatment with snail mucus and edible flower waste extract. We demonstrated that flower waste can be considered a valid candidate for cosmeceutical applications due to its potent antioxidant activity. Thus, a new formulation of snail mucus enriched in extracts of edible flower waste could be useful to design innovative and sustainable broadband natural UV-screen cosmeceutical products.
已有多项研究强调了蜗牛黏液在维持健康皮肤方面的能力，这归因于其具有滋润、再生和保护特性。特别是，已报道从 中提取的黏液具有有益特性，如抗菌活性和伤口修复能力。为了增强蜗牛黏液的有益效果，获得了一种富含抗氧化化合物的配方，这些化合物来自可食用花卉废物（L.、L.、L.、L. 和 Lam.）。使用 UVB 损伤作为模型，研究了蜗牛黏液和可食用花卉提取物的体外细胞保护作用。结果表明，花卉废物提取物中的多酚增强了蜗牛黏液的抗氧化活性，为暴露于 UVB 辐射的角质细胞提供了细胞保护作用。此外，在与蜗牛黏液和可食用花卉废物提取物联合处理后，谷胱甘肽含量、活性氧 (ROS) 和脂质过氧化水平降低。我们证明，由于其强大的抗氧化活性，花卉废物可被视为化妆品应用的有效候选物。因此，富含可食用花卉废物提取物的蜗牛黏液的新配方可能有助于设计创新和可持续的广谱天然 UV 屏蔽化妆品产品。
