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从水曲柳种子中优化超临界 CO2 萃取及其抗疲劳和抗氧化活性。

Optimization of Supercritical Fluid CO Extraction from Yellow Horn Seed and Its Anti-Fatigue and Antioxidant Activity.

机构信息

College of Food Science and Engineering, Beijing University of Agriculture, Beijing 102206, China.

出版信息

Molecules. 2023 Jun 19;28(12):4853. doi: 10.3390/molecules28124853.

DOI:10.3390/molecules28124853
PMID:37375407
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10301247/
Abstract

A supercritical fluid carbon dioxide (SF-CO) extraction method was used to obtain the optimum process for extracting yellow horn seed oil. The anti-fatigue and antioxidant properties of the extracted oil were investigated through animal experiments. The optimum process conditions for SF-CO extraction of the yellow horn oil were 40 MPa, 50 °C and 120 min, with an extraction yield of 31.61%. The high-dose group of yellow horn oil could significantly increase the weight-bearing swimming time, the hepatic glycogen (HG) content and decrease the lactic acid (LA) content and blood urea nitrogen (BUN) content ( < 0.05) in mice. Moreover, it improved the antioxidant ability by reducing the malondialdehyde (MDA) content ( < 0.01) and raising the glutathione reductase (GR) content and superoxide dismutase (SOD) content ( < 0.05) in mice. Yellow horn oil has the effects of being an anti-fatigue and antioxidant substance, which provides a basis for its further utilization and development.

摘要

采用超临界二氧化碳(SF-CO)萃取法,获得提取沙棘籽油的最佳工艺条件。通过动物实验,研究了提取油的抗疲劳和抗氧化性能。SF-CO 萃取沙棘籽油的最佳工艺条件为 40 MPa、50℃和 120 min,萃取收率为 31.61%。高剂量沙棘籽油能显著延长小鼠负重游泳时间,增加肝糖原(HG)含量,降低血乳酸(LA)和血尿素氮(BUN)含量(<0.05)。此外,它还通过降低丙二醛(MDA)含量(<0.01),提高谷胱甘肽还原酶(GR)和超氧化物歧化酶(SOD)含量(<0.05)来提高抗氧化能力。沙棘籽油具有抗疲劳和抗氧化作用,为其进一步利用和开发提供了依据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb0d/10301247/f5c71ea220c2/molecules-28-04853-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb0d/10301247/f051d3ce2343/molecules-28-04853-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb0d/10301247/f5c71ea220c2/molecules-28-04853-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb0d/10301247/f051d3ce2343/molecules-28-04853-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb0d/10301247/f5c71ea220c2/molecules-28-04853-g002.jpg

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