Conesa Celia, Bellés Andrea, Grasa Laura, Sánchez Lourdes
Departamento de Producción Animal y Ciencia de los Alimentos, Facultad de Veterinaria, Universidad de Zaragoza, 50013 Zaragoza, Spain.
Departamento de Farmacología, Fisiología y Medicina Legal y Forense, Facultad de Veterinaria, Universidad de Zaragoza, 50013 Zaragoza, Spain.
Pharmaceutics. 2023 May 23;15(6):1569. doi: 10.3390/pharmaceutics15061569.
The intestine represents one of the first barriers where microorganisms and environmental antigens come into tight contact with the host immune system. A healthy intestine is essential for the well-being of humans and animals. The period after birth is a very important phase of development, as the infant moves from a protected environment in the uterus to one with many of unknown antigens and pathogens. In that period, mother's milk plays an important role, as it contains an abundance of biologically active components. Among these components, the iron-binding glycoprotein, lactoferrin (LF), has demonstrated a variety of important benefits in infants and adults, including the promotion of intestinal health. This review article aims to provide a compilation of all the information related to LF and intestinal health, in infants and adults.
肠道是微生物和环境抗原与宿主免疫系统紧密接触的首要屏障之一。健康的肠道对人类和动物的健康至关重要。出生后的时期是一个非常重要的发育阶段，因为婴儿从子宫内的受保护环境过渡到充满许多未知抗原和病原体的环境。在那个时期，母乳起着重要作用，因为它含有丰富的生物活性成分。在这些成分中，铁结合糖蛋白乳铁蛋白（LF）已在婴儿和成人中显示出多种重要益处，包括促进肠道健康。这篇综述文章旨在汇编所有与婴儿和成人的乳铁蛋白及肠道健康相关的信息。
