Yan Bomin, Zhang Yiwen, Li Zhixiang, Zhou Pinghui, Mao Yingji
School of Life Sciences, Bengbu Medical College, Bengbu, 233030 China.
Department of Plastic Surgery, The First Affiliated Hospital of Bengbu Medical College, Bengbu, 233004 China.
SN Appl Sci. 2022;4(6):172. doi: 10.1007/s42452-022-05056-2. Epub 2022 May 13.
Electrospinning is a simple, cost-effective, flexible, and feasible continuous micro-nano polymer fiber preparation technology that has attracted extensive scientific and industrial interest over the past few decades, owing to its versatility and ability to manufacture highly tunable nanofiber networks. Nanofiber membrane materials prepared using electrospinning have excellent properties suitable for biomedical applications, such as a high specific surface area, strong plasticity, and the ability to manipulate their nanofiber components to obtain the desired properties and functions. With the increasing popularity of nanomaterials in this century, electrospun nanofiber membranes are gradually becoming widely used in various medical fields. Here, the research progress of electrospun nanofiber membrane materials is reviewed, including the basic electrospinning process and the development of the materials as well as their biomedical applications. The main purpose of this review is to discuss the latest research progress on electrospun nanofiber membrane materials and the various new electrospinning technologies that have emerged in recent years for various applications in the medical field. The application of electrospun nanofiber membrane materials in recent years in tissue engineering, wound dressing, cancer diagnosis and treatment, medical protective equipment, and other fields is the main topic of discussion in this review. Finally, the development of electrospun nanofiber membrane materials in the biomedical field is systematically summarized and prospects are discussed. In general, electrospinning has profound prospects in biomedical applications, as it is a practical and flexible technology used for the fabrication of microfibers and nanofibers.
静电纺丝是一种简单、经济高效、灵活且可行的连续微纳聚合物纤维制备技术。在过去几十年中，由于其多功能性以及制造高度可调纳米纤维网络的能力，该技术引起了广泛的科学和工业关注。使用静电纺丝制备的纳米纤维膜材料具有优异的性能，适用于生物医学应用，如高比表面积、强可塑性以及能够操控其纳米纤维成分以获得所需的性能和功能。随着纳米材料在本世纪越来越受欢迎，静电纺纳米纤维膜正逐渐广泛应用于各个医学领域。在此，综述了静电纺纳米纤维膜材料的研究进展，包括基本的静电纺丝过程、材料的发展以及它们的生物医学应用。本综述的主要目的是讨论静电纺纳米纤维膜材料的最新研究进展以及近年来出现的各种新型静电纺丝技术在医学领域的各种应用。静电纺纳米纤维膜材料近年来在组织工程、伤口敷料、癌症诊断与治疗、医疗防护装备等领域的应用是本综述讨论的主要话题。最后，系统总结了静电纺纳米纤维膜材料在生物医学领域的发展并探讨了前景。总体而言，静电纺丝在生物医学应用中具有广阔前景，因为它是一种用于制造微纤维和纳米纤维的实用且灵活的技术。
