Milano Giovanna, Guarducci Giovanni, Nante Nicola, Montomoli Emanuele, Manini Ilaria
Department of Life Sciences, University of Siena, 53100 Siena, Italy.
Post Graduate School of Public Health, University of Siena, 53100 Siena, Italy.
Vaccines (Basel). 2023 Jun 4;11(6):1060. doi: 10.3390/vaccines11061060.
Human papillomavirus (HPV) is sexually transmitted, one of the three most common sexually transmitted infections (STIs) in both males and females, and the most common viral STI. A crucial public health strategy to protect people against HPV is vaccination, which has shown its effectiveness in preventing HPV-related diseases. Presently, three types of vaccines are available (bivalent, quadrivalent, and nonvalent), and they all target the two most oncogenic virus genotypes (HPV 16 and 18). In recent years, the need to implement vaccination programmes that include all genders has been discussed in order to achieve herd immunity against HPV. To date, only a few countries have included young males in their vaccination programmes. Thus, our objective with this review is to provide an overview of the epidemiology of HPV and HPV prevention strategies and report the latest findings from the scientific literature.
人乳头瘤病毒（HPV）通过性传播，是男性和女性中三种最常见的性传播感染（STIs）之一，也是最常见的病毒性性传播感染。保护人们免受HPV感染的一项关键公共卫生策略是接种疫苗，该疫苗已显示出预防HPV相关疾病的有效性。目前有三种类型的疫苗（二价、四价和九价），它们都针对两种最具致癌性的病毒基因型（HPV 16和18）。近年来，为了实现对HPV的群体免疫，人们讨论了实施涵盖所有性别的疫苗接种计划的必要性。迄今为止，只有少数国家将年轻男性纳入其疫苗接种计划。因此，我们进行本次综述的目的是概述HPV的流行病学和HPV预防策略，并报告科学文献中的最新发现。
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