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泰国东北部与麻疹相关的腹泻

Measles-associated diarrhoea in northeastern Thailand.

作者信息

Pongrithsukda V, Phonboon K, Manunpichu K

出版信息

Southeast Asian J Trop Med Public Health. 1986 Mar;17(1):43-7.

PMID:3738607
Abstract

A significant proportion of the illness and death of diarrhoeal diseases in the developing world is estimated to be due to the diarrhoea associated with measles. During February 1983-January 1984 a prospective study of measles in a hospital in Northeastern Thailand was conducted. A total of 550 cases of measles were studied. Diarrhoea was the most frequent complication of measles, occurring in 233 cases (42.4%). The largest proportion (46.2%) of cases with diarrhoea occurred in May-July. Children with measles aged 6-11 months had the highest frequency of diarrhoea (65.7%). Cases aged 1 year and 0-5 months had diarrhoea rates of 60% and 57% respectively. The proportion of measles cases with diarrhoea decreased with increasing age. Only 9.1% (9/99) of stools sent for bacteriological culture were positive. In three of these Shigella spp. were isolated. The rest were non-typhoid Salmonella (2), enteropathogenic Escherichia coli (2), Vibrio cholera (1), and Vibrio parahaemolyticus (1). Other complications among measles cases were pneumonia in 168 (30.5%), otitis media in 28 (5.1%), convulsion in 13 (2.4%), croup in 9 (1.6%), encephalitis in 4 (0.7%), and sepsis in 1 (0.2%). Seven cases (1.3%) died, 4 from pneumonia, 2 from encephalitis, and 1 from sepsis.

摘要

据估计,发展中世界相当一部分腹泻病导致的疾病和死亡是由麻疹相关的腹泻引起的。1983年2月至1984年1月,在泰国东北部的一家医院对麻疹进行了一项前瞻性研究。共研究了550例麻疹病例。腹泻是麻疹最常见的并发症,发生在233例(42.4%)中。腹泻病例中最大比例(46.2%)发生在5月至7月。6至11个月大的麻疹患儿腹泻发生率最高(65.7%)。1岁以及0至5个月大的病例腹泻率分别为60%和57%。麻疹病例中腹泻的比例随着年龄增长而下降。送去进行细菌培养的粪便中只有9.1%(9/99)呈阳性。其中3例分离出志贺菌属。其余的是非伤寒沙门氏菌(2例)、肠致病性大肠杆菌(2例)、霍乱弧菌(1例)和副溶血性弧菌(1例)。麻疹病例中的其他并发症包括肺炎168例(30.5%)、中耳炎28例(5.1%)、惊厥13例(2.4%)、哮吼9例(1.6%)、脑炎4例(0.7%)和败血症1例(0.2%)。7例(1.3%)死亡,4例死于肺炎,2例死于脑炎,1例死于败血症。

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