Alem Orang, Hughes K Jeramy, Buard Isabelle, Cheung Teresa P, Maydew Tyler, Griesshammer Andreas, Holloway Kendall, Park Aaron, Lechuga Vanessa, Coolidge Collin, Gerginov Marja, Quigg Erik, Seames Alexander, Kronberg Eugene, Teale Peter, Knappe Svenja
FieldLine Medical, Boulder, CO, United States.
Paul M. Rady Department of Mechanical Engineering, University of Colorado Boulder, Boulder, CO, United States.
Front Neurosci. 2023 Jun 14;17:1190310. doi: 10.3389/fnins.2023.1190310. eCollection 2023.
Compact optically-pumped magnetometers (OPMs) are now commercially available with noise floors reaching 10 fT/Hz. However, to be used effectively for magnetoencephalography (MEG), dense arrays of these sensors are required to operate as an integrated turn-key system. In this study, we present the HEDscan, a 128-sensor OPM MEG system by FieldLine Medical, and evaluate its sensor performance with regard to bandwidth, linearity, and crosstalk. We report results from cross-validation studies with conventional cryogenic MEG, the Magnes 3,600 WH Biomagnetometer by 4-D Neuroimaging. Our results show high signal amplitudes captured by the OPM-MEG system during a standard auditory paradigm, where short tones at 1000 Hz were presented to the left ear of six healthy adult volunteers. We validate these findings through an event-related beamformer analysis, which is in line with existing literature results.
紧凑型光泵磁力仪（OPM）现已商业化，其本底噪声可达10 fT/Hz。然而，要有效地用于脑磁图（MEG），需要这些传感器的密集阵列作为一个集成的交钥匙系统运行。在本研究中，我们展示了FieldLine Medical公司的128传感器OPM MEG系统HEDscan，并评估了其在带宽、线性度和串扰方面的传感器性能。我们报告了与传统低温MEG（4-D Neuroimaging公司的Magnes 3600 WH生物磁强计）进行交叉验证研究的结果。我们的结果表明，在标准听觉范式中，OPM-MEG系统捕获到高信号幅度，其中向六名健康成年志愿者的左耳呈现1000 Hz的短音。我们通过事件相关波束形成器分析验证了这些发现，这与现有文献结果一致。
